Signal Transduction Antibodies 1

Anti-RALGPS1 Antibody (CAB14827)

(No reviews yet) Write a Review
SKU:
CAB14827
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-RALGPS1 Antibody
Antibody SKU:CAB14827
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat brain, Rat thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MYKR NGLM ASVL VTSA TPQG SSSS DSLE GQSC DYAS KSYD AVVF DVLK VTPE EFAS QITL MDIP VFKA IQPE ELAS CGWS KKEK HSLA PNVV AFTR RFNQ VSFW VVRE ILTA QTLK IRAE ILSH FVKI AKKL LELN NLHS LMSV VSAL QSAP IFRL TKTW ALLN RKDK TTFE KLDY LMSK EDNY KRTR EYIR SLKM VPSI PYLG IYLL DLIY IDSA YPAS GSIM ENEQ RSNQ MNNI LRII ADLQ VSCS YDHL TTLP HVQK YLKS VRYI EELQ KFVE DDNY KLSL RIEP GSSS PRLV SSKE
Gene ID:9649
Uniprot:Q5JS13
Cellular Location:Cell membrane, Cytoplasm
Calculated MW:11kDa/24kDa/34kDa/43kDa/58kDa/59kDa/62kDa
Observed MW:62kDa
Synonyms:RALGPS1, RALGEF2, RALGPS1A
Background:
UniProt Protein Function:RALGPS1: Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for. 6 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GEFs; GEFs, misc.

Chromosomal Location of Human Ortholog: 9q33.3

Cellular Component: cytoplasm; plasma membrane

Molecular Function:Ral guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity

Biological Process: small GTPase mediated signal transduction; regulation of Ral protein signal transduction; positive regulation of GTPase activity

UniProt Code:Q5JS13
NCBI GenInfo Identifier:189040074
NCBI Gene ID:9649
NCBI Accession:Q5JS13.1
UniProt Secondary Accession:Q5JS13,O15059, Q5JT60, Q5JT65, Q5JUG5, Q8N4S6, Q8N5H4 Q8WUV7, Q9NZ16, B4DR86, E9PBQ5,
UniProt Related Accession:Q5JS13
Molecular Weight:59,865 Da
NCBI Full Name:Ras-specific guanine nucleotide-releasing factor RalGPS1
NCBI Synonym Full Names:Ral GEF with PH domain and SH3 binding motif 1
NCBI Official Symbol:RALGPS1  
NCBI Official Synonym Symbols:RALGEF2; RALGPS1A  
NCBI Protein Information:ras-specific guanine nucleotide-releasing factor RalGPS1; RalGEF 2; ralA exchange factor RalGPS1; ral guanine nucleotide exchange factor 2; ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor RalGPS1A
UniProt Protein Name:Ras-specific guanine nucleotide-releasing factor RalGPS1
UniProt Synonym Protein Names:Ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor 2; RalGEF 2; RalA exchange factor RalGPS1
Protein Family:Ras-specific guanine nucleotide-releasing factor
UniProt Gene Name:RALGPS1  
UniProt Entry Name:RGPS1_HUMAN
Anti-RALGPS1 Antibody (CAB14827)Western blot analysis of extracts of various cell lines, using RALGPS1 antibody (CAB14827) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products