Cell Biology Antibodies 5

Anti-RABGGTB Antibody (CAB15310)

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SKU:
CAB15310
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RABGGTB Antibody
Antibody SKU:CAB15310
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human RABGGTB (NP_004573.2).
Application:WB IHC
Recommended Dilution:WB 1:200 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, HeLa, HepG2, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human RABGGTB (NP_004573.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGTP QKDV IIKS DAPD TLLL EKHA DYIA SYGS KKDD YEYC MSEY LRMS GIYW GLTV MDLM GQLH RMNR EEIL AFIK SCQH ECGG ISAS IGHD PHLL YTLS AVQI LTLY DSIN VIDV NKVV EYVK GLQK EDGS FAGD IWGE IDTR FSFC AVAT LALL GKLD AINV EKAI EFVL SCMN FDGG FGCR PGSE SHAG QIYC CTGF LAIT SQLH QVNS DLLG WWLC ERQL PSGG LNGR PEKL PDVC YSWW VLAS LKII GRLH WIDR EKLR NFIL ACQD EETG GFAD RPGD MVDP FHTL FGIA GLSL LGEE QIKP VNPV FCMP EEVL QRVN VQPE LVS
Gene ID:5876
Uniprot:P53611
Cellular Location:
Calculated MW:36kDa
Observed MW:37kDa
Synonyms:RABGGTB, GGTB
Background:This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3.
NCBI Summary:This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]
UniProt Code:P53611
NCBI GenInfo Identifier:18088527
NCBI Gene ID:5876
NCBI Accession:BC020790
UniProt Secondary Accession:P53611,Q92697,
UniProt Related Accession:P53611
Molecular Weight:36,924 Da
NCBI Full Name:Homo sapiens Rab geranylgeranyltransferase, beta subunit, mRNA
NCBI Synonym Full Names:Rab geranylgeranyltransferase beta subunit
NCBI Official Symbol:RABGGTB  
NCBI Official Synonym Symbols:GGTB  
NCBI Protein Information:geranylgeranyl transferase type-2 subunit beta
UniProt Protein Name:
Protein Family:Geranylgeranyl transferase
UniProt Gene Name:
Anti-RABGGTB Antibody (CAB15310)Western blot analysis of extracts of various cell lines, using RABGGTB antibody (CAB15310) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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