Signal Transduction Antibodies 1

Anti-RAB40A Antibody (CAB13236)

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SKU:
CAB13236
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-RAB40A Antibody
Antibody SKU:CAB13236
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB40A (NP_543155.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse lung, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB40A (NP_543155.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSAP GSPD QAYD FLLK FLLV GDRD VGKS EILE SLQD GAAE SPYS HLGG IDYK TTTI LLDG QRVK LKLW DTSG QGRF CTIF RSYS RGAQ GVIL VYDI ANRW SFEG MDRW IKKI EEHA PGVP KILV GNRL HLAF KRQV PREQ AQAY AERL GV
Gene ID:142684
Uniprot:Q8WXH6
Cellular Location:Cell membrane, Cytoplasmic side, Lipid-anchor
Calculated MW:31kDa
Observed MW:31kDa
Synonyms:RAB40A, RAR2, RAR2A
Background:This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box.
UniProt Protein Function:RAB40A: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.
UniProt Protein Details:

Protein type:G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: Xq22.1

NCBI Summary:This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. [provided by RefSeq, Apr 2010]
UniProt Code:Q8WXH6
NCBI GenInfo Identifier:83287759
NCBI Gene ID:142684
NCBI Accession:Q8WXH6.2
UniProt Secondary Accession:Q8WXH6,O00407, Q17RQ5, Q6DK06, Q8TF06,
UniProt Related Accession:Q8WXH6
Molecular Weight:31,076 Da
NCBI Full Name:Ras-related protein Rab-40A
NCBI Synonym Full Names:RAB40A, member RAS oncogene family
NCBI Official Symbol:RAB40A  
NCBI Official Synonym Symbols:RAR2; RAR2A  
NCBI Protein Information:ras-related protein Rab-40A
UniProt Protein Name:Ras-related protein Rab-40A
UniProt Synonym Protein Names:SOCS box-containing protein RAR2A; Protein Rar-2
Protein Family:Ras-related protein
UniProt Gene Name:RAB40A  
UniProt Entry Name:RB40A_HUMAN
Anti-RAB40A Antibody (CAB13236)Western blot analysis of extracts of various cell lines, using RAB40A antibody (CAB13236) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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