Autophagy Antibodies
Anti-RAB39B Antibody (CAB16591)
- SKU:
- CAB16591
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Description
| Antibody Name: | Anti-RAB39B Antibody |
| Antibody SKU: | CAB16591 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human RAB39B (NP_741995.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human RAB39B (NP_741995.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEAI WLYQ FRLI VIGD STVG KSCL IRRF TEGR FAQV SDPT VGVD FFSR LVEI EPGK RIKL QIWD TAGQ ERFR SITR AYYR NSVG GLLL FDIT NRRS FQNV HEWL EETK VHVQ PYQI VFVL VGHK CDLD TQRQ VTRH EAEK LAAA YGMK YIET SARD AINV EKAF TDLT RDIY ELVK RGEI TIQE GWEG VKSG FVPN VVHS SEEV VKSE RRCL C |
| Gene ID: | 116442 |
| Uniprot: | Q96DA2 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Golgi apparatus, Lipid-anchor |
| Calculated MW: | 24kDa |
| Observed MW: | Refer to figures |
| Synonyms: | RAB39B, MRX72, WSMN |
| Background: | This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. |
| UniProt Protein Function: | RAB39B: May be involved in vesicular trafficking. Plays a role in synapse formation. Defects in RAB39B are the cause of mental retardation X- linked type 72 (MRX72). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRX72 patients can manifest autism spectrum disorder, seizures and macrocephaly as additional features. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein, monomeric, Rab; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: Xq28 Cellular Component: Golgi apparatus; intracellular; neuron projection; vesicle Molecular Function:myosin V binding; protein binding Biological Process: synapse organization and biogenesis; vesicle-mediated transport Disease: Mental Retardation, X-linked 72 |
| NCBI Summary: | This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q96DA2 |
| NCBI GenInfo Identifier: | 27734447 |
| NCBI Gene ID: | 116442 |
| NCBI Accession: | Q96DA2.1 |
| UniProt Secondary Accession: | Q96DA2,Q5JT79, Q8NEX3, |
| UniProt Related Accession: | Q96DA2 |
| Molecular Weight: | 24,622 Da |
| NCBI Full Name: | Ras-related protein Rab-39B |
| NCBI Synonym Full Names: | RAB39B, member RAS oncogene family |
| NCBI Official Symbol: | RAB39B |
| NCBI Official Synonym Symbols: | WSMN; MRX72 |
| NCBI Protein Information: | ras-related protein Rab-39B |
| UniProt Protein Name: | Ras-related protein Rab-39B |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB39B |
| UniProt Entry Name: | RB39B_HUMAN |
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