Autophagy Antibodies

Anti-RAB12 Antibody (CAB14320)

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SKU:
CAB14320
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy

Description

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Antibody Name:Anti-RAB12 Antibody
Antibody SKU:CAB14320
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RAB12 (NP_001020471.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:NIH/3T3, Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RAB12 (NP_001020471.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDPG AALQ RRAG GGGG LGAG SPAL SGGQ GRRR KQPP RPAD FKLQ VIII GSRG VGKT SLME RFTD DTFC EA
Gene ID:201475
Uniprot:Q6IQ22
Cellular Location:Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus membrane, Lipid-anchor, Lysosome membrane, Recycling endosome membrane, autophagosome
Calculated MW:27kDa
Observed MW:36kDa
Synonyms:RAB12
Background:
UniProt Protein Function:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
UniProt Code:Q6IQ22
NCBI GenInfo Identifier:106507164
NCBI Gene ID:201475
NCBI Accession:NP_001020471.2
UniProt Secondary Accession:Q6IQ22,Q4KMQ3, A6NEF5,
UniProt Related Accession:Q6IQ22
Molecular Weight:27,248 Da
NCBI Full Name:ras-related protein Rab-12
NCBI Synonym Full Names:RAB12, member RAS oncogene family
NCBI Official Symbol:RAB12  
NCBI Protein Information:ras-related protein Rab-12
UniProt Protein Name:Ras-related protein Rab-12
Protein Family:Ras-related protein
UniProt Gene Name:RAB12  
Anti-RAB12 Antibody (CAB14320)Western blot analysis of extracts of various cell lines, using RAB12 antibody (CAB14320) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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