Name: Anti-RAB11B Antibody (CAB15350)
Brand: Cell Biology Antibodies 6
SKU: CAB15350
Availability: OutOfStock

Antibody Name:	Anti-RAB11B Antibody
Antibody SKU:	CAB15350
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 130-215 of human RAB11B (NP_004209.2).

Application:	WB
Recommended Dilution:	WB 1:200 - 1:2000
Reactivity:	Mouse
Positive Samples:	Mouse pancreas

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 130-215 of human RAB11B (NP_004209.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	HLRA VPTD EARA FAEK NNLS FIET SALD STNV EEAF KNIL TEIY RIVS QKQI ADRA AHDE SPGN NVVD ISVP PTTD GQKP NKLQ CC
Gene ID:	9230
Uniprot:	Q15907
Cellular Location:	Cytoplasmic side, Cytoplasmic vesicle, Lipid-anchor, Recycling endosome membrane, phagosome membrane, secretory vesicle, synaptic vesicle membrane
Calculated MW:	19kDa/24kDa
Observed MW:	24kDa

Synonyms:

RAB11B, H-YPT3

Background:

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

UniProt Protein Function:	RAB11B: GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family.
UniProt Protein Details:	Protein type:G protein, monomeric, Rab; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: synaptic vesicle; recycling endosome; phagocytic vesicle membrane; synaptic vesicle membrane; mitochondrion; recycling endosome membrane; phagocytic vesicle; cell junction Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding Biological Process: receptor recycling; intracellular protein transport; regulated secretory pathway; constitutive secretory pathway; transferrin transport; Rab protein signal transduction; melanosome transport
NCBI Summary:	The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]
UniProt Code:	Q15907
NCBI GenInfo Identifier:	38258938
NCBI Gene ID:	9230
NCBI Accession:	Q15907.4
UniProt Secondary Accession:	Q15907,Q2YDT2, Q5U0I1, Q6FHR0, Q6FI42, Q8NI07, A5YM50 B2R7I4, B4DMK0, D6W671,
UniProt Related Accession:	Q15907
Molecular Weight:	218
NCBI Full Name:	Ras-related protein Rab-11B
NCBI Synonym Full Names:	RAB11B, member RAS oncogene family
NCBI Official Symbol:	RAB11B
NCBI Official Synonym Symbols:	H-YPT3
NCBI Protein Information:	ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B, member of RAS oncogene family
UniProt Protein Name:	Ras-related protein Rab-11B
UniProt Synonym Protein Names:	GTP-binding protein YPT3
Protein Family:	Ras-related protein
UniProt Gene Name:	RAB11B
UniProt Entry Name:	RB11B_HUMAN

Western blot analysis of extracts of Mouse pancreas, using RAB11B antibody (CAB15350) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s.

Antibodies

RAB11B Antibody (PACO05725)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)