Cell Biology Antibodies 9

Anti-RAB10 Antibody (CAB4459)

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SKU:
CAB4459
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RAB10
Research Area:
Cell Biology

Description

Product Name:RAB10 Rabbit pAb
Product Code:CAB4459
Size:20uL, 50uL, 100uL
Synonyms:RAB10
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RAB10 (NP_057215.3).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-87MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RAB10 (NP_057215.3).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAKK TYDL LFKL LLIG DSGV GKTC VLFR FSDD AFNT TFIS TIGI DFKI KTVE LQGK KIKL QIWD TAGQ ERFH TITT SYYR GAMG IMLV YDIT NGKS FENI SKWL RNID EHAN EDVE RMLL GNKC DMDD KRVV PKGK GEQI AREH GIRF FETS AKAN INIE KAFL TLAE DILR KTPV KEPN SENV DISS GG
Gene ID:10890
Uniprot:P61026
Cellular Location:Cell projection, Cytoplasmic side, Cytoplasmic vesicle, Cytoplasmic vesicle membrane, Endoplasmic reticulum membrane, Endosome membrane, Golgi apparatus, Lipid-anchor, Recycling endosome membrane, cilium, phagosome membrane, trans-Golgi network membrane
Calculated MW:22kDa
Observed MW:22kDa
UniProt Protein Function:RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.
UniProt Protein Details:

Protein type:G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: Golgi apparatus; phagocytic vesicle membrane; endoplasmic reticulum membrane; recycling endosome; cytoplasmic vesicle membrane; focal adhesion; recycling endosome membrane; exocyst; plasma membrane; endosome membrane; trans-Golgi network; endosome

Molecular Function:GTPase activity; GDP binding; GTP binding; myosin V binding

Biological Process: metabolic process; establishment of neuroblast polarity; protein secretion; endosome transport; regulation of exocytosis; vesicle-mediated transport; polarized epithelial cell differentiation; intracellular protein transport; Golgi to plasma membrane transport; antigen processing and presentation; cellular response to insulin stimulus; axonogenesis; Golgi to plasma membrane protein transport; Rab protein signal transduction; vesicle docking during exocytosis

NCBI Summary:RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]
UniProt Code:P61026
NCBI GenInfo Identifier:46577638
NCBI Gene ID:10890
NCBI Accession:P61026.1
UniProt Related Accession:P61026
Molecular Weight:22.5kDa
NCBI Full Name:Ras-related protein Rab-10
NCBI Synonym Full Names:RAB10, member RAS oncogene family
NCBI Official Symbol:RAB10  
NCBI Protein Information:ras-related protein Rab-10
UniProt Protein Name:Ras-related protein Rab-10
Protein Family:Ras-related protein
UniProt Gene Name:RAB10  
UniProt Entry Name:RAB10_HUMAN
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