Anti-QSOX1 Antibody (CAB4060)
- SKU:
- CAB4060
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- QSOX1
- Synonyms:
- Q6
- Synonyms:
- QSCN6
Description
| Product Name: | QSOX1 Rabbit pAb |
| Product Code: | CAB4060 |
| Size: | 50uL, 100uL |
| Synonyms: | QSOX1, Q6, QSCN6 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human QSOX1 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | NCI-H460, U-251MG, Mouse heart |
| Immunogen: | Recombinant protein of human QSOX1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5768 |
| Uniprot: | O00391 |
| Cellular Location: | Golgi apparatus membrane, Secreted, Single-pass membrane protein, extracellular space |
| Calculated MW: | 66kDa/82kDa |
| Observed MW: | 66KFa |
| UniProt Protein Function: | quiescin Q6: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.8.3.2; Membrane protein, integral; Oxidoreductase Chromosomal Location of Human Ortholog: 1q24 Cellular Component: Golgi apparatus; extracellular space; intercellular bridge; intracellular membrane-bound organelle; integral to Golgi membrane Molecular Function:protein disulfide isomerase activity; flavin-linked sulfhydryl oxidase activity Biological Process: protein folding; cell redox homeostasis |
| NCBI Summary: | This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00391 |
| NCBI GenInfo Identifier: | 74739466 |
| NCBI Gene ID: | 5768 |
| NCBI Accession: | O00391.3 |
| UniProt Related Accession: | O00391 |
| Molecular Weight: | 83kDa |
| NCBI Full Name: | Sulfhydryl oxidase 1 |
| NCBI Synonym Full Names: | quiescin sulfhydryl oxidase 1 |
| NCBI Official Symbol: | QSOX1 |
| NCBI Official Synonym Symbols: | Q6; QSCN6 |
| NCBI Protein Information: | sulfhydryl oxidase 1 |
| UniProt Protein Name: | Sulfhydryl oxidase 1 |
| UniProt Synonym Protein Names: | Quiescin Q6 |
| Protein Family: | Sulfhydryl oxidase |
| UniProt Gene Name: | QSOX1 |
| UniProt Entry Name: | QSOX1_HUMAN |
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