Cell Biology Antibodies 12

Anti-PTPRZ1 Antibody (CAB9766)

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SKU:
CAB9766
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PTPRZ1 Antibody
Antibody SKU:CAB9766
Antibody Size:100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide of human PTPRZ1
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human
Positive Samples:
Immunogen:A synthetic peptide of human PTPRZ1
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5803
Uniprot:P23471
Cellular Location:Cell membrane, Secreted, Secreted, Single-pass type I membrane protein
Calculated MW:162kDa/253kDa/254kDa
Observed MW:Refer to figures
Synonyms:PTPRZ1, HPTPZ, HPTPzeta, PTP-ZETA, PTP18, PTPRZ, PTPZ, R-PTP-zeta-2, RPTPB, RPTPbeta
Background:This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniProt Protein Function:PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Receptor protein phosphatase, tyrosine; EC 3.1.3.48

Chromosomal Location of Human Ortholog: 7q31.3

Cellular Component: integral to plasma membrane

Molecular Function:protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: central nervous system development; learning and/or memory; oligodendrocyte differentiation; protein amino acid dephosphorylation

Disease: Helicobacter Pylori Infection, Susceptibility To

NCBI Summary:This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
UniProt Code:P23471
NCBI GenInfo Identifier:229485537
NCBI Gene ID:5803
NCBI Accession:P23471.4
UniProt Secondary Accession:P23471,O76043, Q9UDR6, A4D0W5, C9JFM0,
UniProt Related Accession:P23471
Molecular Weight:162,663 Da
NCBI Full Name:Receptor-type tyrosine-protein phosphatase zeta
NCBI Synonym Full Names:protein tyrosine phosphatase, receptor type Z1
NCBI Official Symbol:PTPRZ1  
NCBI Official Synonym Symbols:PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2  
NCBI Protein Information:receptor-type tyrosine-protein phosphatase zeta
UniProt Protein Name:Receptor-type tyrosine-protein phosphatase zeta
UniProt Synonym Protein Names:Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2
Protein Family:Receptor-type tyrosine-protein phosphatase
UniProt Gene Name:PTPRZ1  
UniProt Entry Name:PTPRZ_HUMAN
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