Neuroscience

Anti-PTPN5 Antibody (CAB16585)

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SKU:
CAB16585
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-PTPN5 Antibody
Antibody SKU:CAB16585
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 360-490 of human PTPN5 (NP_116170.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 360-490 of human PTPN5 (NP_116170.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RGYG GEEK VYIA TQGP IVST VADF WRMV WQEH TPII VMIT NIEE MNEK CTEY WPEE QVAY DGVE ITVQ KVIH TEDY RLRL ISLK SGTE ERGL KHYW FTSW PDQK TPDR APPL LHLV REVE EAAQ QEGP HCA
Gene ID:84867
Uniprot:P54829
Cellular Location:Endoplasmic reticulum membrane, Multi-pass membrane protein
Calculated MW:60kDa/63kDa
Observed MW:Refer to figures
Synonyms:PTPN5, PTPSTEP, STEP, STEP61
Background:
UniProt Protein Function:STEP: a non-receptor protein-tyrosine phosphatase. STEP (striatum enriched phosphatase) Contains a single phosphatase catalytic domain located at the C-terminus. Two alternatively-spliced messages have been described.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: integral to membrane

Molecular Function:phosphotyrosine binding; protein binding; protein tyrosine phosphatase activity

Biological Process: protein amino acid dephosphorylation

UniProt Code:P54829
NCBI GenInfo Identifier:317373540
NCBI Gene ID:84867
NCBI Accession:P54829.4
UniProt Secondary Accession:P54829,Q6P1Z2, Q8N2A1, Q8NDP8, B3KXG7, B7Z386, B7ZAF5 D3DQY7,
UniProt Related Accession:P54829
Molecular Weight:60,961 Da
NCBI Full Name:Tyrosine-protein phosphatase non-receptor type 5
NCBI Synonym Full Names:protein tyrosine phosphatase, non-receptor type 5
NCBI Official Symbol:PTPN5  
NCBI Official Synonym Symbols:STEP; STEP61; PTPSTEP  
NCBI Protein Information:tyrosine-protein phosphatase non-receptor type 5
UniProt Protein Name:Tyrosine-protein phosphatase non-receptor type 5
UniProt Synonym Protein Names:Neural-specific protein-tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; STEP
Protein Family:Tyrosine-protein phosphatase non-receptor
UniProt Gene Name:PTPN5  
UniProt Entry Name:PTN5_HUMAN
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