Cell Biology Antibodies 9

Anti-PTPN23 Antibody (CAB4595)

(No reviews yet) Write a Review
SKU:
CAB4595
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PTPN23
Synonyms:
HD-PTP
Synonyms:
HDPTP
Synonyms:
PTP-TD14
Research Area:
Cell Biology

Description

Product Name:PTPN23 Rabbit pAb
Product Code:CAB4595
Size:20uL, 50uL, 100uL
Synonyms:PTPN23, HD-PTP, HDPTP, PTP-TD14
Applications:WB, IHC
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1).
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:Mouse eye, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DSNR VVLR SGKD DYIN ASCV EGLS PYCP PLVA TQAP LPGT AADF WLMV HEQK VSVI VMLV SEAE MEKQ KVAR YFPT ERGQ PMVH GALS LALS SVRS TETH VERV LSLQ FRDQ SLKR SLVH LHFP TWPE LGLP DSPS NLLR FIQE VHAH YLHQ RPLH TPII VHCS SGVG RTGA FALL YAAV QEVE AGNG IPEL PQLV RRMR QQRK HMLQ EKLH LRFC YEAV V
Gene ID:25930
Uniprot:Q9H3S7
Cellular Location:Cytoplasm, Cytoplasmic vesicle, Early endosome, Endosome, Nucleus, cilium basal body, cytoskeleton
Calculated MW:178kDa
Observed MW:179kDa
UniProt Protein Function:PTPN23: May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
UniProt Protein Details:

Protein type:EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: nucleoplasm; cytoplasmic membrane-bound vesicle; cytoplasm; early endosome; nucleus; endosome

Molecular Function:protein binding; protein tyrosine phosphatase activity; protein kinase binding

Biological Process: protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body pathway

UniProt Code:Q9H3S7
NCBI GenInfo Identifier:68053318
NCBI Gene ID:25930
NCBI Accession:Q9H3S7.1
UniProt Secondary Accession:Q9H3S7,Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4 A8K0D7,
UniProt Related Accession:Q9H3S7
Molecular Weight:1636
NCBI Full Name:Tyrosine-protein phosphatase non-receptor type 23
NCBI Synonym Full Names:protein tyrosine phosphatase, non-receptor type 23
NCBI Official Symbol:PTPN23  
NCBI Official Synonym Symbols:HDPTP; HD-PTP; PTP-TD14  
NCBI Protein Information:tyrosine-protein phosphatase non-receptor type 23; protein tyrosine phosphatase TD14; His-domain protein tyrosine phosphatase; his domain-containing protein tyrosine phosphatase
UniProt Protein Name:Tyrosine-protein phosphatase non-receptor type 23
UniProt Synonym Protein Names:His domain-containing protein tyrosine phosphatase; HD-PTP; Protein tyrosine phosphatase TD14; PTP-TD14
Protein Family:Tyrosine-protein phosphatase non-receptor
UniProt Gene Name:PTPN23  
UniProt Entry Name:PTN23_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products