Cell Biology Antibodies 17
Anti-PTGER2 Antibody (CAB9053)
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- SKU:
- CAB9053
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PTGER2 Antibody |
| Antibody SKU: | CAB9053 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PTGER2 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, THP-1, Mouse lung, Mouse liver, Mouse spleen, Rat testis |
| Immunogen: | A synthesized peptide derived from human PTGER2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5732 |
| Uniprot: | P43116 |
| Cellular Location: | |
| Calculated MW: | 52kDa |
| Observed MW: | 52KDa |
| Synonyms: | EP2 |
| Background: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009] |
| UniProt Protein Function: | PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q22 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:prostaglandin E receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation; response to lipopolysaccharide; response to progesterone stimulus Disease: Asthma, Nasal Polyps, And Aspirin Intolerance |
| NCBI Summary: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009] |
| UniProt Code: | P43116 |
| NCBI GenInfo Identifier: | 38258920 |
| NCBI Gene ID: | 5732 |
| NCBI Accession: | P43116.2 |
| UniProt Secondary Accession: | P43116,Q52LG8, D3DSC0, |
| UniProt Related Accession: | P43116 |
| Molecular Weight: | 39,761 Da |
| NCBI Full Name: | Prostaglandin E2 receptor EP2 subtype |
| NCBI Synonym Full Names: | prostaglandin E receptor 2 |
| NCBI Official Symbol: | PTGER2 |
| NCBI Official Synonym Symbols: | EP2 |
| NCBI Protein Information: | prostaglandin E2 receptor EP2 subtype |
| UniProt Protein Name: | Prostaglandin E2 receptor EP2 subtype |
| UniProt Synonym Protein Names: | Prostanoid EP2 receptor |
| Protein Family: | Prostaglandin E2 receptor |
| UniProt Gene Name: | PTGER2 |
| UniProt Entry Name: | PE2R2_HUMAN |
 | Western blot - PTGER2 Rabbit mAb (CAB9053) |
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