Metabolism Antibodies 2
Anti-PSPH Antibody (CAB7924)
- SKU:
- CAB7924
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-PSPH Antibody |
| Antibody SKU: | CAB7924 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human PSPH (NP_004568.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, U-251MG, Jurkat, A-431, Mouse brain, Mouse kidney, Mouse testis, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human PSPH (NP_004568.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVSH SELR KLFY SADA VCFD VDST VIRE EGID ELAK ICGV EDAV SEMT RRAM GGAV PFKA ALTE RLAL IQPS REQV QRLI AEQP PHLT PGIR ELVS RLQE RNVQ VFLI SGGF RSIV EHVA SKLN IPAT NVFA NRLK FYFN GEYA GFDE TQPT AESG GKGK VIKL LKEK FHFK KIIM IGDG ATDM EACP PADA FIGF GGNV IRQQ VKDN AKWY ITDF VELL GELE E |
| Gene ID: | 5723 |
| Uniprot: | P78330 |
| Cellular Location: | |
| Calculated MW: | 25kDa |
| Observed MW: | 25kDa |
| Synonyms: | PSPH, PSP, PSPHD |
| Background: | The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. |
| UniProt Protein Function: | Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. |
| NCBI Summary: | The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P78330 |
| NCBI GenInfo Identifier: | 46249388 |
| NCBI Gene ID: | 5723 |
| NCBI Accession: | NP_004568 |
| UniProt Secondary Accession: | P78330,Q7Z3S5, B2RCR5, |
| UniProt Related Accession: | P78330 |
| Molecular Weight: | 25,008 Da |
| NCBI Full Name: | phosphoserine phosphatase |
| NCBI Synonym Full Names: | phosphoserine phosphatase |
| NCBI Official Symbol: | PSPH |
| NCBI Official Synonym Symbols: | PSP; PSPHD |
| NCBI Protein Information: | phosphoserine phosphatase |
| UniProt Protein Name: | Phosphoserine phosphatase |
| UniProt Synonym Protein Names: | L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase |
| Protein Family: | Psp operon transcriptional activator |
| UniProt Gene Name: | PSPH |
 | Western blot analysis of extracts of various cell lines, using PSPH antibody (CAB7924) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using PSPH antibody (CAB7924) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat brain using PSPH antibody (CAB7924) at dilution of 1:100 (40x lens). |
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