Cell Biology Antibodies 6

Anti-PSMG1 Antibody (CAB15339)

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SKU:
CAB15339
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PSMG1 Antibody
Antibody SKU:CAB15339
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human PSMG1 (NP_003711.1).
Application:WB IHC
Recommended Dilution:WB 1:200 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human PSMG1 (NP_003711.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAT FFGE VVKA PCRA GTED EEEE EEGR RETP EDRE VRLQ LARK REVR LLRR QTKT SLEV SLLE KYPC SKFI IAIG NNAV AFLS SFVM NSGV WEEV GCAK LWNE WCRT TDTT HLSS TEAF CVFY HLKS NPSV FLCQ CSCY VAED QQYQ WLEK VFGS CPRK NMQI TILT CRHV TDYK TSES TGSL PSPF LRAL KTQN FKDS ACCP LLEQ PNIV HDLP AAVL SYCQ VWKI PAIL YLCY TDVM KLDL ITVE AFKP ILST RSLK GLVK NIPQ STEI LKKL MTTN EIQS NIYT
Gene ID:8624
Uniprot:O95456
Cellular Location:Cytoplasm, Endoplasmic reticulum
Calculated MW:30kDa/32kDa
Observed MW:33kDa
Synonyms:PSMG1, C21LRP, DSCR2, LRPC21, PAC-1, PAC1
Background:
UniProt Protein Function:DSCR2: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Belongs to the PSMG1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endoplasmic reticulum; cytoplasm; nucleus

Molecular Function:protein binding

Biological Process: granule cell precursor proliferation; proteasome assembly

UniProt Code:O95456
NCBI GenInfo Identifier:4505023
NCBI Gene ID:8624
NCBI Accession:NP_003711.1
UniProt Secondary Accession:O95456,Q6FHA3, Q6FHD3, Q6S713, B5BUN2,
UniProt Related Accession:O95456
Molecular Weight:30,288 Da
NCBI Full Name:proteasome assembly chaperone 1 isoform a
NCBI Synonym Full Names:proteasome assembly chaperone 1
NCBI Official Symbol:PSMG1  
NCBI Official Synonym Symbols:PAC1; DSCR2; PAC-1; C21LRP; LRPC21  
NCBI Protein Information:proteasome assembly chaperone 1
UniProt Protein Name:Proteasome assembly chaperone 1
UniProt Synonym Protein Names:Chromosome 21 leucine-rich protein; C21-LRP; Down syndrome critical region protein 2
Protein Family:Proteasome assembly chaperone
UniProt Gene Name:PSMG1  
UniProt Entry Name:PSMG1_HUMAN
Anti-PSMG1 Antibody (CAB15339)Western blot analysis of extracts of HeLa cells, using PSMG1 antibody (CAB15339) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5s.
Anti-PSMG1 Antibody (CAB15339)Immunohistochemistry of paraffin-embedded rat spleen using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens).
Anti-PSMG1 Antibody (CAB15339)Immunohistochemistry of paraffin-embedded human appendix using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens).
Anti-PSMG1 Antibody (CAB15339)Immunohistochemistry of paraffin-embedded mouse spleen using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens).
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