Cell Biology Antibodies 10
Anti-PSG1 Antibody (CAB6399)
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- SKU:
- CAB6399
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PSG1 Antibody |
| Antibody SKU: | CAB6399 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1 (NP_001171754.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | A-549, U-251MG, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1 (NP_001171754.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WWMN GQSL PMTH SLKL SETN RTLF LLGV TKYT AGPY ECEI RNPV SASR SDPV TLNL LPKL PKPY ITIN NLNP RENK DVLN FTCE PKSE NYTY IWWL NGQS LPVS PRVK RPIE NRIL ILPS VTRN ETGP YQCE IRDR YGGI RSDP VTLN VLYG PDLP RIYP SFTY YRSG EVLY LSCS ADSN PPAQ YSWT INEK FQLP GQKL FIRH ITTK HSGL YVCS VRNS ATGK ESSK SMTV EVSD WTVP |
| Gene ID: | 5669 |
| Uniprot: | P11464 |
| Cellular Location: | Secreted |
| Calculated MW: | 46kDa/47kDa/48kDa |
| Observed MW: | 55-72kDa |
| Synonyms: | PSG1, B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1 |
| Background: |
| NCBI Summary: | The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009] |
| UniProt Code: | P11464 |
| NCBI GenInfo Identifier: | 129661 |
| NCBI Gene ID: | 5669 |
| NCBI Accession: | P11464.1 |
| UniProt Secondary Accession: | P11464,O75236, P11462, P11463, Q15231, Q15241, Q15243 Q16660, Q6ICR4, Q9P1W5, Q9UQ79, |
| UniProt Related Accession: | P11464 |
| Molecular Weight: | 47,866 Da |
| NCBI Full Name: | Pregnancy-specific beta-1-glycoprotein 1 |
| NCBI Synonym Full Names: | pregnancy specific beta-1-glycoprotein 1 |
| NCBI Official Symbol: | PSG1 |
| NCBI Official Synonym Symbols: | SP1; B1G1; PBG1; CD66f; PSBG1; PSG95; PSGGA; DHFRP2; PSBG-1; PSGIIA; FL-NCA-1/2; PS-beta-C/D; PS-beta-G-1 |
| NCBI Protein Information: | pregnancy-specific beta-1-glycoprotein 1 |
| UniProt Protein Name: | Pregnancy-specific beta-1-glycoprotein 1 |
| UniProt Synonym Protein Names: | CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD_antigen: CD66f |
| Protein Family: | Pregnancy-specific beta-1-glycoprotein |
| UniProt Gene Name: | PSG1 |
 | Western blot analysis of extracts of various cell lines, using PSG1 antibody (CAB6399) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human colon carcinoma using PSG1 antibody (CAB6399) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using PSG1 antibody (CAB6399) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of human placenta cells using PSG1 antibody (CAB6399) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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