Cell Biology Antibodies 13
Anti-PRTN3 Antibody (CAB17522)
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- SKU:
- CAB17522
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PRTN3 Antibody |
| Antibody SKU: | CAB17522 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human PRTN3 (NP_002768.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human PRTN3 (NP_002768.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IVGG HEAQ PHSR PYMA SLQM RGNP GSHF CGGT LIHP SFVL TAAH CLRD IPQR LVNV VLGA HNVR TQEP TQQH FSVA QVFL NNYD AENK LNDV LLIQ LSSP ANLS ASVA TVQL PQQD QPVP HGTQ CLAM GWGR VGAH DPPA QVL |
| Gene ID: | 5657 |
| Uniprot: | P24158 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 25kDa |
 | Western blot - PRTN3 Polyclonal Antibody (CAB17522) |
| Synonyms: | ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3, PRTN3 |
| Background: |
| UniProt Protein Function: | PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily. |
| UniProt Protein Details: | Protein type:EC 3.4.21.76; Cell cycle regulation; Protease Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane Molecular Function:enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: blood coagulation; negative regulation of phagocytosis; positive regulation of cell proliferation |
| UniProt Code: | P24158 |
| NCBI GenInfo Identifier: | 6174926 |
| NCBI Gene ID: | 5657 |
| NCBI Accession: | P24158.3 |
| UniProt Secondary Accession: | P24158,P15637, P18078, Q4VB08, Q4VB09, Q6LBM7, Q6LBN2 Q9UD25, Q9UQD8, |
| UniProt Related Accession: | P24158 |
| Molecular Weight: | 27,807 Da |
| NCBI Full Name: | Myeloblastin |
| NCBI Synonym Full Names: | proteinase 3 |
| NCBI Official Symbol: | PRTN3 |
| NCBI Official Synonym Symbols: | MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA |
| NCBI Protein Information: | myeloblastin |
| UniProt Protein Name: | Myeloblastin |
| UniProt Synonym Protein Names: | AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen |
| Protein Family: | Myeloblastin |
| UniProt Gene Name: | PRTN3 |
| UniProt Entry Name: | PRTN3_HUMAN |
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