Epigenetics & Nuclear Signaling Antibodies 2
Anti-PRPSAP2 Antibody (CAB15711)
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- SKU:
- CAB15711
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-PRPSAP2 Antibody |
| Antibody SKU: | CAB15711 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PRPSAP2 (NP_002758.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse heart, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PRPSAP2 (NP_002758.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MFCV TPPE LETK MNIT KGGL VLFS ANSN SSCM ELSK KIAE RLGV EMGK VQVY QEPN RETR VQIQ ESVR GKDV FIIQ TVSK DVNT TIME LL |
| Gene ID: | 5636 |
| Uniprot: | O60256 |
| Cellular Location: | |
| Calculated MW: | 31kDa/35kDa/36kDa/40kDa |
| Observed MW: | 42kDa |
| Synonyms: | PRPSAP2, PAP41 |
| Background: | This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. |
| NCBI Summary: | This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| UniProt Code: | O60256 |
| NCBI GenInfo Identifier: | 4506133 |
| NCBI Gene ID: | 5636 |
| NCBI Accession: | NP_002758 |
| UniProt Related Accession: | O60256 |
| Molecular Weight: | 31kDa; 35kDa; 36kDa; 40kDa |
| NCBI Full Name: | phosphoribosyl pyrophosphate synthase-associated protein 2 isoform 1 |
| NCBI Synonym Full Names: | phosphoribosyl pyrophosphate synthetase associated protein 2 |
| NCBI Official Symbol: | PRPSAP2 |
| NCBI Official Synonym Symbols: | PAP41 |
| NCBI Protein Information: | phosphoribosyl pyrophosphate synthase-associated protein 2 |
| UniProt Protein Name: | Phosphoribosyl pyrophosphate synthase-associated protein 2 |
| UniProt Synonym Protein Names: | 41 kDa phosphoribosypyrophosphate synthetase-associated protein; PAP41 |
| Protein Family: | Phosphoribosyl pyrophosphate synthase-associated protein |
| UniProt Gene Name: | PRPSAP2 |
 | Western blot analysis of extracts of various cell lines, using PRPSAP2 antibody (CAB15711) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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