Epigenetics & Nuclear Signaling Antibodies 2
Anti-PRPSAP1 Antibody (CAB15710)
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- SKU:
- CAB15710
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-PRPSAP1 Antibody |
| Antibody SKU: | CAB15710 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human PRPSAP1 (NP_002757.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human PRPSAP1 (NP_002757.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNAA RTGY RVFS ANST AACT ELAK RITE RLGA ELGK SVVY QETN GETR VEIK ESVR GQDI FIIQ TIPR DVNT AVME LLIM A |
| Gene ID: | 5635 |
| Uniprot: | Q14558 |
| Cellular Location: | |
| Calculated MW: | 39kDa/42kDa |
| Observed MW: | 42kDa |
| Synonyms: | PRPSAP1, PAP39 |
| Background: |
| UniProt Protein Function: | PRPSAP1: Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Inhibitor Chromosomal Location of Human Ortholog: 17q24-q25 Molecular Function:enzyme inhibitor activity; ribose phosphate diphosphokinase activity; magnesium ion binding; kinase binding Biological Process: negative regulation of kinase activity; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| UniProt Code: | Q14558 |
| NCBI GenInfo Identifier: | 24418495 |
| NCBI Gene ID: | 5635 |
| NCBI Accession: | Q14558.2 |
| UniProt Secondary Accession: | Q14558,Q96H06, B2R6M4, |
| UniProt Related Accession: | Q14558 |
| Molecular Weight: | 356 |
| NCBI Full Name: | Phosphoribosyl pyrophosphate synthase-associated protein 1 |
| NCBI Synonym Full Names: | phosphoribosyl pyrophosphate synthetase-associated protein 1 |
| NCBI Official Symbol: | PRPSAP1 |
| NCBI Official Synonym Symbols: | PAP39 |
| NCBI Protein Information: | phosphoribosyl pyrophosphate synthase-associated protein 1; PRPP synthase-associated protein 1; 39 kDa phosphoribosypyrophosphate synthase-associated protein |
| UniProt Protein Name: | Phosphoribosyl pyrophosphate synthase-associated protein 1 |
| UniProt Synonym Protein Names: | 39 kDa phosphoribosypyrophosphate synthase-associated protein; PAP39 |
| Protein Family: | Phosphoribosyl pyrophosphate synthase-associated protein |
| UniProt Gene Name: | PRPSAP1 |
| UniProt Entry Name: | KPRA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRPSAP1 antibody (CAB15710) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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