Anti-Proteinase 3/PR3 Antibody (CAB19748)
- SKU:
- CAB19748
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ACPA
- Synonyms:
- AGP7
- Synonyms:
- C-ANCA
- Synonyms:
- CANCA
- Synonyms:
- MBN
- Synonyms:
- MBT
- Synonyms:
- NP-4
- Synonyms:
- NP4
- Synonyms:
- P29
- Synonyms:
- PR-3
- Synonyms:
- PR3
- Research Area:
- Cell Biology
Description
| Product Name: | Proteinase 3/PR3 Rabbit mAb |
| Product Code: | CAB19748 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Proteinase 3/PR3 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | A synthesized peptide derived from human Proteinase 3/PR3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5657 |
| Uniprot: | P24158 |
| Calculated MW: | 27kDa |
| Observed MW: | 28KDa |
| UniProt Protein Function: | PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily. |
| UniProt Protein Details: | Protein type:EC 3.4.21.76; Cell cycle regulation; Protease Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane Molecular Function:enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: blood coagulation; negative regulation of phagocytosis; positive regulation of cell proliferation |
| UniProt Code: | P24158 |
| NCBI GenInfo Identifier: | 6174926 |
| NCBI Gene ID: | 5657 |
| NCBI Accession: | P24158.3 |
| UniProt Secondary Accession: | P24158,P15637, P18078, Q4VB08, Q4VB09, Q6LBM7, Q6LBN2 Q9UD25, Q9UQD8, |
| UniProt Related Accession: | P24158 |
| Molecular Weight: | 27,807 Da |
| NCBI Full Name: | Myeloblastin |
| NCBI Synonym Full Names: | proteinase 3 |
| NCBI Official Symbol: | PRTN3 |
| NCBI Official Synonym Symbols: | MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA |
| NCBI Protein Information: | myeloblastin |
| UniProt Protein Name: | Myeloblastin |
| UniProt Synonym Protein Names: | AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen |
| Protein Family: | Myeloblastin |
| UniProt Gene Name: | PRTN3 |
| UniProt Entry Name: | PRTN3_HUMAN |
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