Cell Biology Antibodies 15

Anti-PRM2 Antibody (CAB6704)

(No reviews yet) Write a Review
SKU:
CAB6704
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PRM2 Antibody
Antibody SKU:CAB6704
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human PRM2 (NP_002753.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human PRM2 (NP_002753.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MVRY RVRS LSER SHEV YRQQ LHGQ EQGH HGQE EQGL SPEH VEVY ERTH GQSH YRRR HCSR RRLH RIHR RQHR SCRR RKRR SCRH RRRH RRGC RTRK RTCR RH
Gene ID:5620
Uniprot:P04554
Cellular Location:Chromosome, Nucleus
Calculated MW:13kDa/17kDa
Observed MW:Refer to figures
Synonyms:PRM2, CT94.2
Background:Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene.
UniProt Protein Function:PRM2: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P2 family.
UniProt Protein Details:

Protein type:Cancer Testis Antigen (CTA); DNA-binding

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: nucleoplasm; nucleosome; nucleus

Molecular Function:cadmium ion binding; DNA binding; zinc ion binding

Biological Process: chromosome condensation; DNA packaging; multicellular organism development; nucleus organization; spermatid development; spermatogenesis

UniProt Code:P04554
NCBI GenInfo Identifier:886877
NCBI Gene ID:
NCBI Accession:CAA87066.1
UniProt Secondary Accession:P04554,Q6ZMM0,
Molecular Weight:17,106 Da
NCBI Full Name:protamine 2
UniProt Protein Name:Protamine-2
UniProt Synonym Protein Names:Sperm histone P2; Sperm protamine P2
UniProt Gene Name:PRM2  
View AllClose

0 Reviews

View AllClose

Related Products