Cell Biology Antibodies 1
Anti-PRLHR Antibody (CAB10479)
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- SKU:
- CAB10479
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PRLHR Antibody |
| Antibody SKU: | CAB10479 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human PRLHR (NP_004239.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HepG2, U-87MG, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human PRLHR (NP_004239.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASS TTRG PRVS DLFS GLPP AVTT PANQ SAEA SAGN GSVA GADA PAVT PFQS LQLV HQLK GLIV LLYS VV |
| Gene ID: | 2834 |
| Uniprot: | P49683 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 41kDa |
| Synonyms: | PRLHR, GPR10, GR3, PrRPR |
| Background: |
| UniProt Protein Function: | GPR10: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 10q26.13 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide receptor activity; neuropeptide Y receptor activity; protein binding Biological Process: cell surface receptor linked signal transduction; feeding behavior; female pregnancy; G-protein coupled receptor protein signaling pathway; hormone metabolic process; neuropeptide signaling pathway |
| NCBI Summary: | PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P49683 |
| NCBI GenInfo Identifier: | 311033415 |
| NCBI Gene ID: | 2834 |
| NCBI Accession: | P49683.3 |
| UniProt Secondary Accession: | P49683,O75194, Q502U8, Q5VXR9, |
| UniProt Related Accession: | P49683 |
| Molecular Weight: | 41,121 Da |
| NCBI Full Name: | Prolactin-releasing peptide receptor |
| NCBI Synonym Full Names: | prolactin releasing hormone receptor |
| NCBI Official Symbol: | PRLHR |
| NCBI Official Synonym Symbols: | GR3; GPR10; PrRPR |
| NCBI Protein Information: | prolactin-releasing peptide receptor |
| UniProt Protein Name: | Prolactin-releasing peptide receptor |
| UniProt Synonym Protein Names: | G-protein coupled receptor 10; hGR3 |
| Protein Family: | Prolactin-releasing peptide receptor |
| UniProt Gene Name: | PRLHR |
| UniProt Entry Name: | PRLHR_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRLHR antibody (CAB10479) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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