Cell Biology Antibodies 15

Anti-PRKG2 Antibody (CAB18575)

(No reviews yet) Write a Review
SKU:
CAB18575
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PRKG2 Antibody
Antibody SKU:CAB18575
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human PRKG2.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse lung, Rat brain
Immunogen:Recombinant protein of human PRKG2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5593
Uniprot:Q13237
Cellular Location:Apical cell membrane, Lipid-anchor
Calculated MW:84kDa/87kDa
Observed MW:100kDa
Anti-PRKG2 Antibody (CAB18575)Western blot - PRKG2 Rabbit pAb (CAB18575)
Synonyms:PRKGR2, cGK2, cGKII, PRKG2
Background:This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:PKG2: an AGC kinase of the PKG family. Type II cGMP-dependent protein kinase is expressed at high levels in brain, lung and intestinal mucosa.
UniProt Protein Details:

Protein type:Kinase, protein; Protein kinase, AGC; EC 2.7.11.12; Protein kinase, Ser/Thr (non-receptor); AGC group; PKG family

Chromosomal Location of Human Ortholog: 4q13.1-q21.1

Cellular Component: apical plasma membrane; cytosol; nuclear membrane

Molecular Function:ATP binding; cGMP binding; cGMP-dependent protein kinase activity; protein homodimerization activity; protein kinase activity

Biological Process: blood coagulation; circadian regulation of gene expression; nitric oxide metabolic process; protein amino acid phosphorylation; regulation of nitric-oxide synthase activity; signal transduction

NCBI Summary:This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:Q13237
NCBI GenInfo Identifier:6226833
NCBI Gene ID:5593
NCBI Accession:Q13237.1
UniProt Secondary Accession:Q13237,O00125, O60916, B4DMX3, E7EPE6,
UniProt Related Accession:Q13237
Molecular Weight:84,398 Da
NCBI Full Name:cGMP-dependent protein kinase 2
NCBI Synonym Full Names:protein kinase, cGMP-dependent, type II
NCBI Official Symbol:PRKG2  
NCBI Official Synonym Symbols:cGK2; cGKII; PRKGR2  
NCBI Protein Information:cGMP-dependent protein kinase 2
UniProt Protein Name:cGMP-dependent protein kinase 2
UniProt Synonym Protein Names:cGMP-dependent protein kinase II; cGKII
Protein Family:cGMP-dependent protein kinase
UniProt Gene Name:PRKG2  
UniProt Entry Name:KGP2_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products