Cell Biology Antibodies 13
Anti-PRKCDBP Antibody (CAB17247)
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- SKU:
- CAB17247
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PRKCDBP Antibody |
| Antibody SKU: | CAB17247 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-160 of human PRKCDBP (NP_659477.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-160 of human PRKCDBP (NP_659477.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SNTL AQLL AKAE RVSS HANA AQER AVRR AAQV QRLE ANHG LLVA RGKL HVLL FKEE GEVP ASAF QKAP EPLG PADQ SELG PEQL EA |
| Gene ID: | 112464 |
| Uniprot: | Q969G5 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 27kDa |
| Observed MW: | 35kDa |
 | Western blot - PRKCDBP Rabbit pAb (CAB17247) |
| Synonyms: | CAVIN3, HSRBC, PRKCDBP, SRBC, cavin-3 |
| Background: | The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. |
| UniProt Protein Function: | PRKCDBP: Seems to have an immune potentiation function. Belongs to the PTRF/SDPR family. |
| UniProt Protein Details: | Protein type:Tumor suppressor Chromosomal Location of Human Ortholog: 11p15.4 Cellular Component: protein complex; cytoplasm; caveola Molecular Function:protein binding; protein kinase C binding Biological Process: negative regulation of protein kinase B signaling cascade; cortical actin cytoskeleton organization and biogenesis; circadian regulation of gene expression |
| NCBI Summary: | The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q969G5 |
| NCBI GenInfo Identifier: | 317373527 |
| NCBI Gene ID: | 112464 |
| NCBI Accession: | Q969G5.3 |
| UniProt Related Accession: | Q969G5 |
| Molecular Weight: | 261 |
| NCBI Full Name: | Protein kinase C delta-binding protein |
| NCBI Synonym Full Names: | protein kinase C, delta binding protein |
| NCBI Official Symbol: | PRKCDBP |
| NCBI Official Synonym Symbols: | SRBC; HSRBC; CAVIN3; cavin-3 |
| NCBI Protein Information: | protein kinase C delta-binding protein; sdr-related gene product that binds to c-kinase; serum deprivation response factor-related gene product that binds to C-kinase |
| UniProt Protein Name: | Protein kinase C delta-binding protein |
| UniProt Synonym Protein Names: | Cavin-3; Serum deprivation response factor-related gene product that binds to C-kinase; hSRBC |
| Protein Family: | Protein kinase C delta-binding protein |
| UniProt Gene Name: | PRKCDBP |
| UniProt Entry Name: | PRDBP_HUMAN |
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