Cell Biology Antibodies 14
Anti-PRIM1 Antibody (CAB16959)
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- SKU:
- CAB16959
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PRIM1 Antibody |
| Antibody SKU: | CAB16959 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 121-420 of human PRIM1 (NP_000937.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 121-420 of human PRIM1 (NP_000937.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CCSS ADIC PKCW TLMT MAIR IIDR ALKE DFGF KHRL WVYS GRRG VHCW VCDE SVRK LSSA VRSG IVEY LSLV KGGQ DVKK KVHL SEKI HPFI RKSI NIIK KYFE EYAL VNQD ILEN KESW DKIL ALVP ETIH DELQ QSFQ KSHN SLQR WEHL KKVA SRYQ NNIK NDKY GPWL EWEI MLQY CFPR LDIN VSKG INHL LKSP FSVH PKTG RISV PIDL QKVD QFDP FTVP TISF ICRE LDAI STNE EEKE ENEA ESDV KHRT RDYK KTSL APYV KVFE HFLE NLDK SRKG ELLK KSDL QKDF |
| Gene ID: | 5557 |
| Uniprot: | P49642 |
| Cellular Location: | |
| Calculated MW: | 49kDa |
| Observed MW: | 49kDa |
 | Western blot - PRIM1 Rabbit pAb (CAB16959) |
| Synonyms: | PRIM1, p49 |
| Background: | The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. |
| UniProt Protein Function: | PRIM1: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Heterodimer of a small subunit and a large subunit. Belongs to the eukaryotic-type primase small subunit family. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Transferase; EC 2.7.7.-; DNA replication Chromosomal Location of Human Ortholog: 12q13 Cellular Component: nucleoplasm; membrane Molecular Function:DNA primase activity; metal ion binding Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; telomere maintenance via recombination; DNA replication, synthesis of RNA primer; DNA strand elongation during DNA replication; mitotic cell cycle; telomere maintenance; G1/S transition of mitotic cell cycle |
| NCBI Summary: | The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P49642 |
| NCBI GenInfo Identifier: | 4506051 |
| NCBI Gene ID: | 5557 |
| NCBI Accession: | NP_000937.1 |
| UniProt Related Accession: | P49642 |
| Molecular Weight: | 65.9 kDa |
| NCBI Full Name: | DNA primase small subunit |
| NCBI Synonym Full Names: | primase, DNA, polypeptide 1 (49kDa) |
| NCBI Official Symbol: | PRIM1 |
| NCBI Official Synonym Symbols: | p49 |
| NCBI Protein Information: | DNA primase small subunit; DNA primase 1; primase p49 subunit; DNA primase subunit 48; DNA primase 49 kDa subunit; primase polypeptide 1, 49kDa |
| UniProt Protein Name: | DNA primase small subunit |
| UniProt Synonym Protein Names: | DNA primase 49 kDa subunit; p49 |
| UniProt Gene Name: | PRIM1 |
| UniProt Entry Name: | PRI1_HUMAN |
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