Cell Biology Antibodies 15
Anti-PRELP Antibody (CAB18573)
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- SKU:
- CAB18573
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PRELP Antibody |
| Antibody SKU: | CAB18573 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PRELP. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse lung, Rat heart |
| Immunogen: | Recombinant protein of human PRELP. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5549 |
| Uniprot: | P51888 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 44KDa |
 | `- PRELP Polyclonal Antibody (CAB18573) |
| Synonyms: | MST161, MSTP161, SLRR2A, PRELP |
| Background: |
| UniProt Protein Function: | PRELP: May anchor basement membranes to the underlying connective tissue. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted Chromosomal Location of Human Ortholog: 1q32 Cellular Component: extracellular matrix; extracellular region; extracellular space; Golgi lumen; lysosomal lumen Molecular Function:heparin binding Biological Process: axonogenesis; keratan sulfate biosynthetic process; keratan sulfate catabolic process; skeletal development |
| NCBI Summary: | The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51888 |
| NCBI GenInfo Identifier: | 1709586 |
| NCBI Gene ID: | 5549 |
| NCBI Accession: | P51888.1 |
| UniProt Secondary Accession: | P51888,Q6FG38, |
| UniProt Related Accession: | P51888 |
| Molecular Weight: | 43,810 Da |
| NCBI Full Name: | Prolargin |
| NCBI Synonym Full Names: | proline and arginine rich end leucine rich repeat protein |
| NCBI Official Symbol: | PRELP |
| NCBI Official Synonym Symbols: | MST161; SLRR2A; MSTP161 |
| NCBI Protein Information: | prolargin |
| UniProt Protein Name: | Prolargin |
| UniProt Synonym Protein Names: | Proline-arginine-rich end leucine-rich repeat protein |
| Protein Family: | Prolargin |
| UniProt Gene Name: | PRELP |
| UniProt Entry Name: | PRELP_HUMAN |
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