Metabolism Antibodies 3

Anti-PRDX6 Antibody (CAB4286)

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SKU:
CAB4286
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism

Description

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Antibody Name:Anti-PRDX6 Antibody
Antibody SKU:CAB4286
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human PRDX6
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, 293T, Mouse liver, Mouse kidney, Rat lung, Rat liver, Rat kidney
Immunogen:A synthesized peptide derived from human PRDX6
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9588
Uniprot:P30041
Cellular Location:
Calculated MW:25kDa
Observed MW:25KDa
Synonyms:1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29
Background:The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
UniProt Protein Function:PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.
UniProt Protein Details:

Protein type:Amino Acid Metabolism - phenylalanine; Oxidoreductase; Energy Metabolism - methane; EC 1.11.1.9; EC 1.11.1.15; Phospholipase

Chromosomal Location of Human Ortholog: 1q25.1

Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol

Molecular Function:antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity

Biological Process: response to reactive oxygen species; phospholipid catabolic process; hydrogen peroxide catabolic process; response to oxidative stress

NCBI Summary:The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
UniProt Code:P30041
NCBI GenInfo Identifier:1718024
NCBI Gene ID:9588
NCBI Accession:P30041.3
UniProt Secondary Accession:P30041,P32077, Q5TAH4, Q5ZEZ8, A8JZY7,
UniProt Related Accession:P30041
Molecular Weight:Observed: 27kDaCalculated: 25kDa
NCBI Full Name:Peroxiredoxin-6
NCBI Synonym Full Names:peroxiredoxin 6
NCBI Official Symbol:PRDX6  
NCBI Official Synonym Symbols:PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m  
NCBI Protein Information:peroxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm binding protein Li 128m
UniProt Protein Name:Peroxiredoxin-6
UniProt Synonym Protein Names:1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.-); aiPLA2; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase (EC:1.11.1.9); NSGPx; Red blood cells page spot 12
Protein Family:Peroxiredoxin
UniProt Gene Name:PRDX6  
UniProt Entry Name:PRDX6_HUMAN
Anti-PRDX6 Antibody (CAB4286)Western blot - PRDX6 Rabbit mAb (CAB4286)
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