Cell Biology Antibodies 13
Anti-PRDM12 Antibody (CAB17746)
- SKU:
- CAB17746
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-PRDM12 Antibody |
Antibody SKU: | CAB17746 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-330 of human PRDM12 (NP_067632.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | U-87MG |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-330 of human PRDM12 (NP_067632.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LGIF SKTW IKAG TEMG PFTG RVIA PEHV DICK NNNL MWEV FNED GTVR YFID ASQE DHRS WMTY IKCA RNEQ EQNL EVVQ IGTS IFYK AIEM IPPD QELL VWYG NSHN TFLG IPGV PGLE EDQK KNKH EDFH PADS AAGP AGRM RCVI CHRG FNSR SNLR SHMR IHTL DKPF VCRF CNRR FSQS STLR NHVR LHTG ERPY KCQV CQSA YSQL AGLR AHQK SARH RPPS TAL |
Gene ID: | 59335 |
Uniprot: | Q9H4Q4 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 45kDa |
Synonyms: | HSAN8, PFM9, PRDM12 |
Background: | This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017] |
UniProt Code: | Q9H4Q4 |
NCBI GenInfo Identifier: | 15042949 |
NCBI Gene ID: | 59335 |
NCBI Accession: | NP_067632.2 |
UniProt Secondary Accession: | Q9H4Q4,A3KFK9, |
UniProt Related Accession: | Q9H4Q4 |
Molecular Weight: | |
NCBI Full Name: | PR domain zinc finger protein 12 |
NCBI Synonym Full Names: | PR domain containing 12 |
NCBI Official Symbol: | PRDM12 |
NCBI Official Synonym Symbols: | PFM9 |
NCBI Protein Information: | PR domain zinc finger protein 12 |
UniProt Protein Name: | PR domain zinc finger protein 12 |
UniProt Synonym Protein Names: | PR domain-containing protein 12 |
Protein Family: | PR domain zinc finger protein |
UniProt Gene Name: | PRDM12 |
UniProt Entry Name: | PRD12_HUMAN |