Epigenetics & Nuclear Signaling Antibodies 2
Anti-PRDM10 Antibody (CAB15176)
- SKU:
- CAB15176
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-PRDM10 Antibody |
Antibody SKU: | CAB15176 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-870 of human PRDM10 (NP_064613.2). |
Application: | IF |
Recommended Dilution: | IF 1:50 - 1:200 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-870 of human PRDM10 (NP_064613.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LDLL KDHV AIHI NDGY FTCP TCKK RFPD FIQV KKHV RSFH SEKI YQCT ECDK AFCR PDKL RLHM LRHS DRKD FLCS TCGK QFKR KDKL REHM QRMH NPER EAKK ADRI SRSK TFKP RITS TDYD SFTF KCRL CMMG FRRR GMLV NHLS KRHP DMKI EEVP ELTL PIIK PNRD YFCQ YCDK VYKS ASKR KAHI LKNH PGAE LPPS IRKL RPAG PGEP DPML STHT QLTG TIAT PPVC CPHC SKQY SSKT KMVQ HIRK KHPE FAQL SNTI HTP |
Gene ID: | 56980 |
Uniprot: | Q9NQV6 |
Cellular Location: | Nucleus |
Calculated MW: | 116kDa/120kDa/121kDa/130kDa/131kDa/137kDa |
Observed MW: |
Synonyms: | PRDM10, PFM7 |
Background: | The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
UniProt Protein Function: | PRDM10: May be involved in transcriptional regulation. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Methyltransferase, protein lysine, predicted; C2H2-type zinc finger protein; Transcription regulation Chromosomal Location of Human Ortholog: 11q25 Molecular Function:protein binding |
NCBI Summary: | The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NQV6 |
NCBI GenInfo Identifier: | 442570289 |
NCBI Gene ID: | 56980 |
NCBI Accession: | Q9NQV6.3 |
UniProt Secondary Accession: | Q9NQV6,Q17R90, Q2KHR4, Q863Z2, Q9NXI4, Q9ULI9, B7ZL71 G3XAE5, J3KP23, |
UniProt Related Accession: | Q9NQV6 |
Molecular Weight: | 131,349 Da |
NCBI Full Name: | PR domain zinc finger protein 10 |
NCBI Synonym Full Names: | PR/SET domain 10 |
NCBI Official Symbol: | PRDM10 |
NCBI Official Synonym Symbols: | PFM7 |
NCBI Protein Information: | PR domain zinc finger protein 10 |
UniProt Protein Name: | PR domain zinc finger protein 10 |
UniProt Synonym Protein Names: | PR domain-containing protein 10; Tristanin |
Protein Family: | PR domain zinc finger protein |
UniProt Gene Name: | PRDM10 |
UniProt Entry Name: | PRD10_HUMAN |
Immunofluorescence analysis of U2OS cells using PRDM10 antibody (CAB15176) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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