Cell Biology Antibodies 7

Anti-PRB4 Antibody (CAB16701)

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SKU:
CAB16701
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PRB4 Antibody
Antibody SKU:CAB16701
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 178-247 of human PRB4 (NP_002714.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:293T, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 178-247 of human PRB4 (NP_002714.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SPPG KPQG PPQQ EGNK PQGP PPPG KPQG PPPA GGNP QQPQ APPA GKPQ GPPP PPQG GRPP RPAQ GQQP PQ
Gene ID:5545
Uniprot:P10163
Cellular Location:
Calculated MW:31kDa
Observed MW:31kDa
Synonyms:PRB4, Po
Background:This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Small" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
UniProt Protein Function:PRB4:
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: extracellular region

NCBI Summary:This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Small" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Nov 2015]
UniProt Code:P10163
NCBI GenInfo Identifier:635377465
NCBI Gene ID:5545
NCBI Accession:P10163.4
UniProt Secondary Accession:P10163,O00600, P02813, P10161, P10162, P81489, A1L439
UniProt Related Accession:P10163
Molecular Weight:31,326 Da
NCBI Full Name:Basic salivary proline-rich protein 4
NCBI Synonym Full Names:proline rich protein BstNI subfamily 4
NCBI Official Symbol:PRB4  
NCBI Official Synonym Symbols:Po  
NCBI Protein Information:basic salivary proline-rich protein 4
UniProt Protein Name:Basic salivary proline-rich protein 4
UniProt Synonym Protein Names:Parotid o protein; Salivary proline-rich protein II-1
Protein Family:Basic salivary proline-rich protein
UniProt Gene Name:PRB4  
Anti-PRB4 Antibody (CAB16701)Western blot analysis of extracts of various cell lines, using PRB4 antibody (CAB16701) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
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