Cell Biology Antibodies 7
Anti-PPP6R3 Antibody (CAB17177)
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- SKU:
- CAB17177
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PPP6R3 Antibody |
| Antibody SKU: | CAB17177 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MFWK FDLH SSSH IDTL LERE DVTL KELM DEED VLQE CKAQ NRKL IEFL LKAE CLED LVSF IIEE PPQD MDEK IRYK YPNI SCEL LTSD VSQM NDRL GEDE SLLM KLYS FLLN DSPL NPLL ASFF SKVL SILI SRKP EQIV DFLK KKHD FVDL IIKH IGTS AIMD LLLR LLTC IEPP QPRQ DVLN WLNE EKII QRLV EIVH PSQE EDRH SNAS QSLC EIVR LSRD QMLQ IQNS TEPD PLLA TLEK QEII EQLL SNIF HKEK |
| Gene ID: | 55291 |
| Uniprot: | Q5H9R7 |
| Cellular Location: | |
| Calculated MW: | 88kDa/94kDa/96kDa/97kDa/98kDa |
| Observed MW: | Refer to figures |
| Synonyms: | PPP6R3, C11orf23, PP6R3, SAP190, SAPL, SAPLa, SAPS3 |
| Background: | Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]). |
| NCBI Summary: | Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q5H9R7 |
| NCBI GenInfo Identifier: | 255918196 |
| NCBI Gene ID: | 55291 |
| NCBI Accession: | NP_001157634 |
| UniProt Related Accession: | Q5H9R7 |
| Molecular Weight: | 130140 |
| NCBI Full Name: | serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform 1 |
| NCBI Synonym Full Names: | protein phosphatase 6 regulatory subunit 3 |
| NCBI Official Symbol: | PPP6R3 |
| NCBI Official Synonym Symbols: | SAPL; PP6R3; SAPLa; SAPS3; SAP190; C11orf23 |
| NCBI Protein Information: | serine/threonine-protein phosphatase 6 regulatory subunit 3 |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 6 regulatory subunit 3 |
| UniProt Synonym Protein Names: | SAPS domain family member 3; Sporulation-induced transcript 4-associated protein SAPL |
| UniProt Gene Name: | PPP6R3 |
| UniProt Entry Name: | PP6R3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPP6R3 antibody (CAB17177) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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