Epigenetics & Nuclear Signaling Antibodies 1

Anti-PPP5C Antibody (CAB11712)

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SKU:
CAB11712
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-PPP5C Antibody
Antibody SKU:CAB11712
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PPP5C (NP_006238.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, Hela, NCI-H460, Mouse kidney, Mouse brain, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PPP5C (NP_006238.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAMA EGER TECA EPPR DEPP ADGA LKRA EELK TQAN DYFK AKDY ENAI KFYS QAIE LNPS NAIY YGNR SLAY LRTE CYGY ALGD ATRA IELD KKYI KGYY RRAA SNMA LGKF RAAL RDYE TVVK VKPH DKDA KMKY QECN KIVK QKAF ERAI AGDE HKRS VVDS LDIE SMTI EDEY SGPK LEDG KVTI SFMK ELMQ WYKD QKKL HRKC AY
Gene ID:5536
Uniprot:P53041
Cellular Location:Cytoplasm, Membrane, Nucleus
Calculated MW:56kDa
Observed MW:57kDa
Synonyms:PPP5C, PP5, PPP5, PPT
Background:This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
NCBI Summary:This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
UniProt Code:P53041
NCBI GenInfo Identifier:12805032
NCBI Gene ID:5536
NCBI Accession:BC001970
UniProt Secondary Accession:P53041,Q16722, Q53XV2,
UniProt Related Accession:P53041
Molecular Weight:56,879 Da
NCBI Full Name:Homo sapiens protein phosphatase 5, catalytic subunit, mRNA
NCBI Synonym Full Names:protein phosphatase 5 catalytic subunit
NCBI Official Symbol:PPP5C  
NCBI Official Synonym Symbols:PP5; PPT; PPP5  
NCBI Protein Information:serine/threonine-protein phosphatase 5
UniProt Protein Name:
UniProt Gene Name:
Anti-PPP5C Antibody (CAB11712)Western blot analysis of extracts of various cell lines, using PPP5C Antibody (CAB11712) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
Anti-PPP5C Antibody (CAB11712)Immunofluorescence analysis of HeLa cells using PPP5C Polyclonal Antibody (CAB11712) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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