Cell Biology Antibodies 5

Anti-PPP2R5E Antibody (CAB15084)

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SKU:
CAB15084
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PPP2R5E Antibody
Antibody SKU:CAB15084
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 398-467 of human PPP2R5E (NP_006237.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, Jurkat, NIH/3T3, mouse thymus, mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 398-467 of human PPP2R5E (NP_006237.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HWNP AIVA LVYN VLKA FMEM NSTM FDEL TATY KSDR QREK KKEK EREE LWKK LEDL ELKR GLRR DGII PT
Gene ID:5529
Uniprot:Q16537
Cellular Location:Cytoplasm
Calculated MW:46kDa/54kDa
Observed MW:54kDa
Synonyms:PPP2R5E, B56E, B56epsilon
Background:The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene.
UniProt Protein Function:PPP2R5E: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B56 family.
UniProt Protein Details:

Protein type:Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q23.1

Cellular Component: cytoplasm

Molecular Function:protein binding

NCBI Summary:The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
UniProt Code:Q16537
NCBI GenInfo Identifier:7387498
NCBI Gene ID:5529
NCBI Accession:Q16537.1
UniProt Secondary Accession:Q16537,Q52LW4, A4FU37, B7ZAW5, B7ZKK8, B7ZKK9, J3KQN6
UniProt Related Accession:Q16537
Molecular Weight:46,180 Da
NCBI Full Name:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
NCBI Synonym Full Names:protein phosphatase 2 regulatory subunit B'epsilon
NCBI Official Symbol:PPP2R5E  
NCBI Protein Information:serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
UniProt Protein Name:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
UniProt Synonym Protein Names:PP2A B subunit isoform B'-epsilon; PP2A B subunit isoform B56-epsilon; PP2A B subunit isoform PR61-epsilon; PP2A B subunit isoform R5-epsilon
Protein Family:Serine/threonine-protein phosphatase
UniProt Gene Name:PPP2R5E  
UniProt Entry Name:2A5E_HUMAN
Anti-PPP2R5E Antibody (CAB15084)Western blot analysis of extracts of various cell lines, using PPP2R5E antibody (CAB15084) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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