Cell Biology Antibodies 18

Anti-PPP2R3A Antibody (CAB18320)

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SKU:
CAB18320
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PPP2R3A Antibody
Antibody SKU:CAB18320
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human PPP2R3A.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant protein of human PPP2R3A.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5523
Uniprot:Q06190
Cellular Location:
Calculated MW:
Observed MW:
Synonyms:PPP2R3, PR130, PR72, PPP2R3A
Background:
UniProt Protein Function:PPP2R3A: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: protein phosphatase type 2A complex

Molecular Function:protein binding; protein phosphatase type 2A regulator activity; calcium ion binding

Biological Process: regulation of catalytic activity; positive regulation of protein catabolic process; eye photoreceptor cell differentiation; protein amino acid dephosphorylation; somatic muscle development

NCBI Summary:This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]
UniProt Code:Q06190
NCBI GenInfo Identifier:543720
NCBI Gene ID:5523
NCBI Accession:Q06190.1
UniProt Related Accession:Q06190
Molecular Weight:
NCBI Full Name:Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
NCBI Synonym Full Names:protein phosphatase 2 regulatory subunit B''alpha
NCBI Official Symbol:PPP2R3A  
NCBI Official Synonym Symbols:PR72; PR130; PPP2R3  
NCBI Protein Information:serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
UniProt Protein Name:Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
UniProt Synonym Protein Names:PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B''-PR72/PR130; PP2A subunit B isoforms B72/B130; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B
UniProt Gene Name:PPP2R3A  
UniProt Entry Name:P2R3A_HUMAN
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