Anti-PPP1R3C Antibody (CAB20458)

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SKU:
CAB20458
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PTG
Synonyms:
PPP1R5

Description

Product Name:PPP1R3C Rabbit pAb
Product Code:CAB20458
Size:50uL, 100uL
Synonyms:PTG, PPP1R5
Applications:IHC, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human PPP1R3C.
Applications:IHC, IF
Recommended Dilutions:IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein of human PPP1R3C.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5507
Uniprot:Q9UQK1
Calculated MW:36kDa
Observed MW:Refer to figures
UniProt Protein Function:Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
UniProt Protein Details:
NCBI Summary:This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]
UniProt Code:Q9UQK1
NCBI GenInfo Identifier:4885559
NCBI Gene ID:5507
NCBI Accession:NP_005389.1
UniProt Secondary Accession:Q9UQK1,O95686, B2R7X0
UniProt Related Accession:Q9UQK1
Molecular Weight:36,445 Da
NCBI Full Name:protein phosphatase 1 regulatory subunit 3C
NCBI Synonym Full Names:protein phosphatase 1 regulatory subunit 3C
NCBI Official Symbol:PPP1R3C  
NCBI Official Synonym Symbols:PTG; PPP1R5  
NCBI Protein Information:protein phosphatase 1 regulatory subunit 3C
UniProt Protein Name:Protein phosphatase 1 regulatory subunit 3C
UniProt Synonym Protein Names:Protein phosphatase 1 regulatory subunit 5; PP1 subunit R5; Protein targeting to glycogen; PTG
Protein Family:
UniProt Gene Name:PPP1R3C  
UniProt Entry Name:
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