Cell Biology Antibodies 15
Anti-PPP1R1C Antibody (CAB18550)
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- SKU:
- CAB18550
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PPP1R1C Antibody |
| Antibody SKU: | CAB18550 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PPP1R1C. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human PPP1R1C. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 151242 |
| Uniprot: | Q8WVI7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | IPP5, PPP1R1C |
| Background: |
| UniProt Protein Function: | PPP1R1C: Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis. Belongs to the protein phosphatase inhibitor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q31.3 Cellular Component: cytoplasm Molecular Function:protein phosphatase inhibitor activity; type 1 serine/threonine specific protein phosphatase inhibitor activity Biological Process: negative regulation of protein kinase activity; positive regulation of cell growth |
| NCBI Summary: | Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010] |
| UniProt Code: | Q8WVI7 |
| NCBI GenInfo Identifier: | 74730857 |
| NCBI Gene ID: | 151242 |
| NCBI Accession: | Q8WVI7.1 |
| UniProt Secondary Accession: | Q8WVI7,Q5HYJ5, Q8TD54, |
| UniProt Related Accession: | Q8WVI7 |
| Molecular Weight: | 13,138 Da |
| NCBI Full Name: | Protein phosphatase 1 regulatory subunit 1C |
| NCBI Synonym Full Names: | protein phosphatase 1 regulatory inhibitor subunit 1C |
| NCBI Official Symbol: | PPP1R1C |
| NCBI Official Synonym Symbols: | IPP5 |
| NCBI Protein Information: | protein phosphatase 1 regulatory subunit 1C |
| UniProt Protein Name: | Protein phosphatase 1 regulatory subunit 1C |
| UniProt Synonym Protein Names: | Inhibitor-5 of protein phosphatase 1; IPP5 |
| Protein Family: | Protein phosphatase 1 regulatory |
| UniProt Gene Name: | PPP1R1C |
| UniProt Entry Name: | PPR1C_HUMAN |
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