Description
| Product Name: | Anti-PPP1R18 Antibody |
| Product Sku: | MACO0333 |
| Size: | 100ul |
| Host Species: | Mouse |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Purified recombinant human PPP1R18 protein fragments expressed in E.coli. |
| Form: | Liquid |
| Storage Buffer: | Ascites |
| Purification Method: | Affinity purified |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Conjugate: | Non-conjugated |
| Background: | May target protein phosphatase 1 to F-actin cytoskeleton. |
| Synonyms: | HKMT1098; KIAA1949; Protein phosphatase 1 F actin cytoskeleton targeting subunit; PPP1R18; |
| UniProt Protein Function: | PPP1R18: May target protein phosphatase 1 to F-actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 6p21.3 Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6NYC8 |
| NCBI GenInfo Identifier: | 68052323 |
| NCBI Gene ID: | 170954 |
| NCBI Accession: | Q6NYC8.1 |
| UniProt Secondary Accession: | Q6NYC8,Q68CK8, Q6ZTV1, Q6ZUJ6, Q8NDQ4, Q8TF52, A2AB01 A2AIB8, A4UBI6, A6NCB7 |
| UniProt Related Accession: | Q6NYC8 |
| Molecular Weight: | 17,771 Da |
| NCBI Full Name: | Phostensin |
| NCBI Synonym Full Names: | protein phosphatase 1 regulatory subunit 18 |
| NCBI Official Symbol: | PPP1R18 |
| NCBI Official Synonym Symbols: | HKMT1098; KIAA1949 |
| NCBI Protein Information: | phostensin |
| UniProt Protein Name: | Phostensin |
| UniProt Synonym Protein Names: | Protein phosphatase 1 F-actin cytoskeleton-targeting subunit; Protein phosphatase 1 regulatory subunit 18 |
| Protein Family: | Phostensin |
| UniProt Gene Name: | PPP1R18 |
| UniProt Entry Name: | PPR18_HUMAN |