Cell Biology Antibodies 13
Anti-PPP1R12B Antibody (CAB17510)
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- SKU:
- CAB17510
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PPP1R12B Antibody |
| Antibody SKU: | CAB17510 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T, U-87MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TFSR SRAE RQAQ EQPR EKPT DTEG LEGS PEKH EPSA VPAT EAGE GQQP WGRS LDEE PICH RLRC PAQP DKPT TPAS PSTS RPSL YTSS HLLW TNRF SVPD SESS ETTT NTTT AKEM DKNE NEEA DLDE QSSK RLSI RERR RPKE RRRG TGIN FWTK DEDE TDGS EEVK ETWH ERLS RLES GGSN PTTS DSYG DRAS ARAR REAR EARL ATLT SRVE EDSN RDYK KLYE SALT ENQK LKTK LQEA QLEL ADIK SKLE KVAQ QKQE KTSD RSS |
| Gene ID: | 4660 |
| Uniprot: | O60237 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 110kDa |
 | Western blot - PPP1R12B Polyclonal Antibody (CAB17510) |
| Synonyms: | MYPT2, PP1bp55, PPP1R12B |
| Background: | Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011] |
| UniProt Code: | O60237 |
| NCBI GenInfo Identifier: | 268607506 |
| NCBI Gene ID: | 4660 |
| NCBI Accession: | NP_002472.2 |
| UniProt Secondary Accession: | O60237,Q2TAI8, Q5T506, Q5VUK2, Q8N179, Q9HCB7, Q9HCB8 A8MYF5, B7ZMN6, |
| UniProt Related Accession: | O60237 |
| Molecular Weight: | 110,404 Da |
| NCBI Full Name: | protein phosphatase 1 regulatory subunit 12B isoform a |
| NCBI Synonym Full Names: | protein phosphatase 1, regulatory subunit 12B |
| NCBI Official Symbol: | PPP1R12B |
| NCBI Official Synonym Symbols: | MYPT2; PP1bp55 |
| NCBI Protein Information: | protein phosphatase 1 regulatory subunit 12B; myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 2; protein phosphatase 1, regulatory (inhibitor) subunit 12B |
| UniProt Protein Name: | Protein phosphatase 1 regulatory subunit 12B |
| UniProt Synonym Protein Names: | Myosin phosphatase-targeting subunit 2 |
| UniProt Gene Name: | PPP1R12B |
| UniProt Entry Name: | MYPT2_HUMAN |
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