Signal Transduction Antibodies 2
Anti-PPIL-4 Antibody (CAB15920)
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- SKU:
- CAB15920
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | PPIL4 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB15920 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-492 of human PPIL4 (NP_624311.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | 293T, U-87MG, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-492 of human PPIL4 (NP_624311.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDNV LIDD RRIH VDFS QSVA KVKW KGKG GKYT KSDF KEYE KEQD KPPN LVLK DKVK PKQD TKYD LILD EQAE DSKS SHSH TSKK HKKK THHC SEEK EDED YMPI KNTN QDIY REMG FGHY EEEE SCWE KQKS EKRD RTQN RSRS RSRE RDGH YSNS HKSK YQTD LYER ERSK KRDR SRSP KKSK DKEK SKYR |
| Gene ID: | 85313 |
| Uniprot: | Q8WUA2 |
| Cellular Location: | Nucleus |
| Calculated MW: | 57kDa |
| Observed MW: | 65kDa |
| Synonyms: | PPIL4, HDCME13P |
| Background: | This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. |
| UniProt Protein Function: | PPIL4: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily. |
| UniProt Protein Details: | Protein type:Isomerase; RNA-binding; EC 5.2.1.8; Cyclophilin Chromosomal Location of Human Ortholog: 6q25.1 Cellular Component: cytoplasm; nucleoplasm Molecular Function:peptidyl-prolyl cis-trans isomerase activity |
| NCBI Summary: | This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WUA2 |
| NCBI GenInfo Identifier: | 74760546 |
| NCBI Gene ID: | 85313 |
| NCBI Accession: | Q8WUA2.1 |
| UniProt Secondary Accession: | Q8WUA2,Q7Z3Q5, B2RD34, |
| UniProt Related Accession: | Q8WUA2 |
| Molecular Weight: | 57,225 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase-like 4 |
| NCBI Synonym Full Names: | peptidylprolyl isomerase like 4 |
| NCBI Official Symbol: | PPIL4 |
| NCBI Official Synonym Symbols: | HDCME13P |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase-like 4 |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase-like 4 |
| UniProt Synonym Protein Names: | Cyclophilin-like protein PPIL4; Rotamase PPIL4 |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIL4 |
| UniProt Entry Name: | PPIL4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPIL4 antibody (CAB15920) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of U-2 OS cells using PPIL4 antibody (CAB15920) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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