Epigenetics & Nuclear Signaling Antibodies 2
Anti-PPIL-1 Antibody (CAB14892)
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- SKU:
- CAB14892
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | PPIL1 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB14892 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human PPIL1 (NP_057143.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, HeLa, Raji, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat lung, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human PPIL1 (NP_057143.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAI PPDS WQPP NVYL ETSM GIIV LELY WKHA PKTC KNFA ELAR RGYY NGTK FHRI IKDF MIQG GDPT GTGR GGAS IYGK QFED ELHP DLKF TGAG ILAM ANAG PDTN GSQF FVTL APTQ WLDG KHTI FGRV CQGI GMVN RVGM VETN SQDR PVDD VKII KAYP SG |
| Gene ID: | 51645 |
| Uniprot: | Q9Y3C6 |
| Cellular Location: | |
| Calculated MW: | 18kDa |
| Observed MW: | 18kDa |
| Synonyms: | PPIL1, CGI-124, CYPL1, PPIase, hCyPX |
| Background: | This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| UniProt Protein Function: | PPIL1: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily. |
| UniProt Protein Details: | Protein type:Isomerase; Spliceosome; EC 5.2.1.8; Cyclophilin Chromosomal Location of Human Ortholog: 6p21.1 Molecular Function:peptidyl-prolyl cis-trans isomerase activity; protein binding Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y3C6 |
| NCBI GenInfo Identifier: | 20177874 |
| NCBI Gene ID: | 51645 |
| NCBI Accession: | Q9Y3C6.1 |
| UniProt Secondary Accession: | Q9Y3C6,O15001, Q5TDC9, |
| UniProt Related Accession: | Q9Y3C6 |
| Molecular Weight: | 18,237 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase-like 1 |
| NCBI Synonym Full Names: | peptidylprolyl isomerase like 1 |
| NCBI Official Symbol: | PPIL1 |
| NCBI Official Synonym Symbols: | CYPL1; hCyPX; PPIase; CGI-124 |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase-like 1 |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase-like 1 |
| UniProt Synonym Protein Names: | Rotamase PPIL1 |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIL1 |
| UniProt Entry Name: | PPIL1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPIL1 antibody (CAB14892) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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