Cell Biology Antibodies 12

Anti-PPIC Antibody (CAB9837)

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SKU:
CAB9837
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PPIC Antibody
Antibody SKU:CAB9837
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-212 of human PPIC (NP_000934.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human
Positive Samples:HeLa, MCF7, SW480, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-212 of human PPIC (NP_000934.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SSGA EGFR KRGP SVTA KVFF DVRI GDKD VGRI VIGL FGKV VPKT VENF VALA TGEK GYGY KGSK FHRV IKDF MIQG GDIT TGDG TGGV SIYG ETFP DENF KLKH YGIG WVSM ANAG PDTN GSQF FITL TKPT WLDG KHVV FGKV IDGM TVVH SIEL QATD GHDR PLTN CSII NSGK IDVK TPFV VEIA DW
Gene ID:5480
Uniprot:P45877
Cellular Location:Cytoplasm
Calculated MW:22kDa
Observed MW:23kDa
Synonyms:PPIC, CYPC
Background:The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A.
UniProt Protein Function:PPIC: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family.
UniProt Protein Details:

Protein type:EC 5.2.1.8; Isomerase; Cyclophilin

Chromosomal Location of Human Ortholog: 5q23.2

Molecular Function:cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity; protein binding

NCBI Summary:The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]
UniProt Code:P45877
NCBI GenInfo Identifier:1169178
NCBI Gene ID:5480
NCBI Accession:P45877.1
UniProt Secondary Accession:P45877,A4LBB5,
UniProt Related Accession:P45877
Molecular Weight:22,763 Da
NCBI Full Name:Peptidyl-prolyl cis-trans isomerase C
NCBI Synonym Full Names:peptidylprolyl isomerase C
NCBI Official Symbol:PPIC  
NCBI Official Synonym Symbols:CYPC  
NCBI Protein Information:peptidyl-prolyl cis-trans isomerase C
UniProt Protein Name:Peptidyl-prolyl cis-trans isomerase C
UniProt Synonym Protein Names:Cyclophilin C; Rotamase C
Protein Family:Peptidyl-prolyl cis-trans isomerase
UniProt Gene Name:PPIC  
UniProt Entry Name:PPIC_HUMAN
Anti-PPIC Polyclonal Antibody (CAB9837)Western blot analysis of extracts of various cell lines, using PPIC antibody (CAB9837) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-PPIC Polyclonal Antibody (CAB9837)Immunohistochemistry of paraffin-embedded human prostate using PPIC antibody (CAB9837) at dilution of 1:100 (40x lens).
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