Anti-PP2A alpha + beta Antibody (CAB6175)
- SKU:
- CAB6175
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PP2Abeta
- Synonyms:
- PP2CB
- Research Area:
- Cell Biology
Description
| Product Name: | PP2A alpha + beta Rabbit mAb |
| Product Code: | CAB6175 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PP2Abeta, PP2CB |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PP2A alpha + beta |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, NIH/3T3, Jurkat, C6, Mouse testis, Mouse brain, Rat lung, Rat testis |
| Immunogen: | A synthesized peptide derived from human PP2A alpha + beta |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5516/5515 |
| Uniprot: | P62714/P67775 |
| Calculated MW: | 36kDa |
| Observed MW: | 36kDa |
| UniProt Protein Function: | PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. |
| UniProt Protein Details: | Protein type:Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16 Chromosomal Location of Human Ortholog: 8p12 Cellular Component: spindle pole; protein phosphatase type 2A complex; nucleus; cytosol; chromosome, pericentric region Molecular Function:protein C-terminus binding; protein binding; metal ion binding; protein serine/threonine phosphatase activity Biological Process: response to antibiotic; proteasomal ubiquitin-dependent protein catabolic process; apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; response to hydrogen peroxide; regulation of gene expression; negative regulation of Ras protein signal transduction; protein amino acid dephosphorylation |
| NCBI Summary: | This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P62714 |
| NCBI GenInfo Identifier: | 50402236 |
| NCBI Gene ID: | 5516 |
| NCBI Accession: | P62714.1 |
| UniProt Secondary Accession: | P62714,P67775, P62715, P63330, P62716 P63331, |
| UniProt Related Accession: | P62714 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| NCBI Synonym Full Names: | protein phosphatase 2 catalytic subunit beta |
| NCBI Official Symbol: | PPP2CB |
| NCBI Official Synonym Symbols: | PP2CB; PP2Abeta |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| Protein Family: | PP2A regulatory |
| UniProt Gene Name: | PPP2CB |
| UniProt Entry Name: | PP2AB_HUMAN |
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