Cell Biology Antibodies 5

Anti-POMGNT2 Antibody (CAB14518)

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SKU:
CAB14518
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-POMGNT2 Antibody
Antibody SKU:CAB14518
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human POMGNT2 (NP_116195.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, 293T, BxPC-3, A-549, Mouse ovary, Mouse brain, Mouse pancreas, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human POMGNT2 (NP_116195.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NPDN LMHV FHDD LLPL FYTL RQFP GLAH EARL FFME GWGE GAHF DLYK LLSP KQPL LRAQ LKTL GRLL CFSH AFVG LSKI TTWY QYGF VQPQ GPKA NILV SGNE IRQF ARFM TEKL NVSH TGVP LGEE YILV FSRT QNRL ILNE AELL LALA QEFQ MKTV TVSL EDHT FADV VRLV SNAS M
Gene ID:84892
Uniprot:Q8NAT1
Cellular Location:Endoplasmic reticulum membrane, Single-pass type II membrane protein
Calculated MW:66kDa
Observed MW:75kDa
Synonyms:POMGNT2, AGO61, C3orf39, GTDC2, MDDGA8
Background:This gene encodes a protein with glycosyltransferase activity although its function is not currently known.
UniProt Protein Function:AGO61: a protein with glycosyltransferase activity although its function is not currently known. [provided by RefSeq, Sep 2012]
UniProt Protein Details:

Protein type:EC 2.4.-.-; Secreted; Transferase; Secreted, signal peptide; EC 2.4.1.255

Chromosomal Location of Human Ortholog: 3p22.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function:acetylglucosaminyltransferase activity

Biological Process: protein amino acid O-linked glycosylation; protein amino acid O-linked mannosylation; neuron migration

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 8

NCBI Summary:This gene encodes a protein with glycosyltransferase activity although its function is not currently known. [provided by RefSeq, Sep 2012]
UniProt Code:Q8NAT1
NCBI GenInfo Identifier:74729999
NCBI Gene ID:84892
NCBI Accession:Q8NAT1.1
UniProt Secondary Accession:Q8NAT1,Q96SY3, B3KWC3,
UniProt Related Accession:Q8NAT1
Molecular Weight:580
NCBI Full Name:Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
NCBI Synonym Full Names:protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
NCBI Official Symbol:POMGNT2  
NCBI Official Synonym Symbols:AGO61; GTDC2; MDDGA8; C3orf39  
NCBI Protein Information:protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2; glycosyltransferase-like domain containing 2; glycosyltransferase-like domain-containing protein 2
UniProt Protein Name:Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
UniProt Synonym Protein Names:Extracellular O-linked N-acetylglucosamine transferase-like; Glycosyltransferase-like domain-containing protein 2
Protein Family:Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase
UniProt Gene Name:POMGNT2  
UniProt Entry Name:PMGT2_HUMAN
Anti-POMGNT2 Antibody (CAB14518)Western blot analysis of extracts of various cell lines, using POMGNT2 antibody (CAB14518) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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