Epigenetics & Nuclear Signaling Antibodies 2
Anti-POLDIP2 Antibody (CAB15812)
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- SKU:
- CAB15812
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-POLDIP2 Antibody |
| Antibody SKU: | CAB15812 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human POLDIP2 (NP_056399.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, HepG2, HeLa, Mouse heart, Mouse kidney |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human POLDIP2 (NP_056399.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGMR EAQN SHVY WWRY CIRL ENLD SDVV QLRE RHWR IFSL SGTL ETVR GRGV VGRE PVLS KEQP AFQY SSHV SLQA SSGH MWGT FRFE RPDG SHFD VRIP P |
| Gene ID: | 26073 |
| Uniprot: | Q9Y2S7 |
| Cellular Location: | Nucleus |
| Calculated MW: | 42kDa |
| Observed MW: | 38kDa |
| Synonyms: | POLDIP2, PDIP38, POLD4, p38 |
| Background: | This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | POLDIP2: Interacts with PCNA and POLD2. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: mitochondrion; nucleus Molecular Function:DNA binding |
| NCBI Summary: | This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| UniProt Code: | Q9Y2S7 |
| NCBI GenInfo Identifier: | 50401206 |
| NCBI Gene ID: | 26073 |
| NCBI Accession: | Q9Y2S7.1 |
| UniProt Related Accession: | Q9Y2S7 |
| Molecular Weight: | |
| NCBI Full Name: | Polymerase delta-interacting protein 2 |
| NCBI Synonym Full Names: | DNA polymerase delta interacting protein 2 |
| NCBI Official Symbol: | POLDIP2 |
| NCBI Official Synonym Symbols: | p38; POLD4; PDIP38 |
| NCBI Protein Information: | polymerase delta-interacting protein 2 |
| UniProt Protein Name: | Polymerase delta-interacting protein 2 |
| UniProt Synonym Protein Names: | 38 kDa DNA polymerase delta interaction protein; p38 |
| UniProt Gene Name: | POLDIP2 |
| UniProt Entry Name: | PDIP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using POLDIP2 antibody (CAB15812) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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