Cell Biology Antibodies 11
Anti-POC1A Antibody (CAB7465)
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- SKU:
- CAB7465
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-POC1A Antibody |
| Antibody SKU: | CAB7465 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 138-407 of human POC1A (NP_056241.3). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HL-60, NCI-H460, SKOV3, Raji |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 138-407 of human POC1A (NP_056241.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LFSL SQHI NWVR CAKF SPDG RLIV SASD DKTV KLWD KSSR ECVH SYCE HGGF VTYV DFHP SGTC IAAA GMDN TVKV WDVR THRL LQHY QLHS AAVN GLSF HPSG NYLI TASS DSTL KILD LMEG RLLY TLHG HQGP ATTV AFSR TGEY FASG GSDE QVMV WKSN FDIV DHGE VTKV PRPP ATLA SSMG NLPE VDFP VPPG RGRS VESV QSQP QEPV SVPQ TLTS TLEH IVGQ LDVL TQTV SILE QRLT LTED KLKQ CLEN QQLI MQRA TP |
| Gene ID: | 25886 |
| Uniprot: | Q8NBT0 |
| Cellular Location: | Cytoplasm, centriole, centrosome, cilium basal body, cytoskeleton, microtubule organizing center, spindle pole |
| Calculated MW: | 39kDa/40kDa/45kDa |
| Observed MW: | 45kDa |
| Synonyms: | POC1A, PIX2, SOFT, WDR51A |
| Background: | POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. |
| UniProt Protein Function: | WDR51A: POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p21.2 Cellular Component: centriole; centrosome; spindle pole Molecular Function:protein binding Disease: Short Stature, Onychodysplasia, Facial Dysmorphism, And Hypotrichosis |
| NCBI Summary: | POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012] |
| UniProt Code: | Q8NBT0 |
| NCBI GenInfo Identifier: | 91207986 |
| NCBI Gene ID: | 25886 |
| NCBI Accession: | Q8NBT0.2 |
| UniProt Secondary Accession: | Q8NBT0,Q0VDF8, Q2TAK6, Q96IK6, Q9UFJ8, A4FUW4, E9PFC6 |
| UniProt Related Accession: | Q8NBT0 |
| Molecular Weight: | 40,936 Da |
| NCBI Full Name: | POC1 centriolar protein homolog A |
| NCBI Synonym Full Names: | POC1 centriolar protein A |
| NCBI Official Symbol: | POC1A |
| NCBI Official Synonym Symbols: | PIX2; SOFT; WDR51A |
| NCBI Protein Information: | POC1 centriolar protein homolog A |
| UniProt Protein Name: | POC1 centriolar protein homolog A |
| UniProt Synonym Protein Names: | Pix2; Proteome of centriole protein 1A; WD repeat-containing protein 51A |
| Protein Family: | POC1 centriolar protein |
| UniProt Gene Name: | POC1A |
| UniProt Entry Name: | POC1A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using POC1A antibody (CAB7465) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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