Metabolism Antibodies 1
Anti-PNLIPRP2 Antibody (CAB12895)
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- SKU:
- CAB12895
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-PNLIPRP2 Antibody |
| Antibody SKU: | CAB12895 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-470 of human PNLIPRP2 (NP_005387.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:1000 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-470 of human PNLIPRP2 (NP_005387.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LGYP CASY DEFQ ESKC FPCP AEGC PKMG HYAD QFKG KTSA VEQT FFLN TGES GNFT SWRY KVSV TLSG KEKV NGYI RIAL YGSN ENSK QYEI FKGS LKPD ASHT CAID VDFN VGKI QKVK FLWN KRGI NLSE PKLG ASQI TVQS GEDG TEYN FCSS DTVE ENVL QSLY PC |
| Gene ID: | 5408 |
| Uniprot: | P54317 |
| Cellular Location: | Secreted |
| Calculated MW: | 51kDa |
| Observed MW: | 54kDa |
| Synonyms: | PNLIPRP2, PLRP2 |
| Background: | This gene encodes a lipase that hydrolyzes galactolipids, the main components of plant membrane lipids. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. |
| UniProt Protein Function: | PNLIPRP2: Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis. Belongs to the AB hydrolase superfamily. Lipase family. |
| UniProt Protein Details: | Protein type:EC 3.1.1.26; EC 3.1.1.3; Lipase; Lipid Metabolism - glycerolipid; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: extracellular region; extracellular space Molecular Function:acylglycerol lipase activity; calcium ion binding; galactolipase activity; phospholipase activity; triacylglycerol lipase activity Biological Process: galactolipid catabolic process; lipid digestion; phospholipid catabolic process; triacylglycerol metabolic process |
| NCBI Summary: | This gene encodes a lipase that hydrolyzes galactolipids, the main components of plant membrane lipids. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P54317 |
| NCBI GenInfo Identifier: | 1708840 |
| NCBI Gene ID: | 5408 |
| NCBI Accession: | P54317.1 |
| UniProt Secondary Accession: | P54317,Q6IB55, A8K627, |
| UniProt Related Accession: | P54317 |
| Molecular Weight: | 52kDa |
| NCBI Full Name: | Pancreatic lipase-related protein 2 |
| NCBI Synonym Full Names: | pancreatic lipase related protein 2 (gene/pseudogene) |
| NCBI Official Symbol: | PNLIPRP2 |
| NCBI Official Synonym Symbols: | PLRP2 |
| NCBI Protein Information: | pancreatic lipase-related protein 2 |
| UniProt Protein Name: | Pancreatic lipase-related protein 2 |
| UniProt Synonym Protein Names: | Galactolipase |
| Protein Family: | Pancreatic lipase-related protein |
| UniProt Gene Name: | PNLIPRP2 |
 | Western blot analysis of extracts of rat pancreas, using PNLIPRP2 antibody (CAB12895) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunofluorescence analysis of rat pancreas using PNLIPRP2 antibody (CAB12895) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse pancreas using PNLIPRP2 antibody (CAB12895) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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