Anti-PMEL Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0264)

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SKU:
HDAB0264
Product Type:
Rabbit Monoclonal Antibody
Antibody Type:
Monoclonal Antibody
Size:
100 μg
Reactivity:
Human
Host Species:
Rabbit
Antibody Isotype:
Rabbit/Human Fc chimeric IgG1
Clone:
DMC420
Synonyms:
D12S53E, gp100, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV

Description

system_update_altDatasheet
SKU:HDAB0264
Size:100 µg
Clonality:Monoclonal
Clone:DMC420
Synonyms:D12S53E, gp100, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV
Applications:Flow Cyt
Recommended Dilution:Flow Cyt 1:100
Host Species:Rabbit
Isotype:Rabbit/Human Fc chimeric IgG1
Reactivity:Human
Purification Method:Purified from cell culture supernatant by affinity chromatography
Formulation:Powder
Buffer:1XPBS
Storage:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:Research use only
Background:This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
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