Anti-PLXND1 Antibody (CAB20239)

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SKU:
CAB20239
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PLEXD1

Description

Product Name:PLXND1 Rabbit pAb
Product Code:CAB20239
Size:50uL, 100uL
Synonyms:PLEXD1
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human PLXND1.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant protein of human PLXND1.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:23129
Uniprot:Q9Y4D7
Calculated MW:212kDa
Observed MW:Refer to figures
UniProt Protein Function:PLXND1: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. Belongs to the plexin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: integral to plasma membrane; lamellipodium; plasma membrane Molecular Function: protein binding; protein domain specific binding; semaphorin receptor activity Biological Process: angiogenesis; branchiomotor neuron axon guidance; endothelial cell migration; regulation of angiogenesis; regulation of axon extension involved in axon guidance; regulation of cell migration; synaptogenesis
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9Y4D7
NCBI GenInfo Identifier:296452982
NCBI Gene ID:23129
NCBI Accession:Q9Y4D7.3
UniProt Secondary Accession:Q9Y4D7,Q6PJS9, Q8IZJ2, Q9BTQ2, A7E2C6, C9JPZ6
UniProt Related Accession:Q9Y4D7
Molecular Weight:195,558 Da
NCBI Full Name:Plexin-D1
NCBI Synonym Full Names:plexin D1
NCBI Official Symbol:PLXND1  
NCBI Official Synonym Symbols:PLEXD1  
NCBI Protein Information:plexin-D1
UniProt Protein Name:Plexin-D1
UniProt Synonym Protein Names:
Protein Family:Plexin
UniProt Gene Name:PLXND1  
UniProt Entry Name:PLXD1_HUMAN
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