Cell Biology Antibodies 1

Anti-PLXNA2 Antibody (CAB10087)

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SKU:
CAB10087
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PLXNA2 Antibody
Antibody SKU:CAB10087
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-560 of human PLXNA2 (NP_079455.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, Mouse brain, Mouse lung, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-560 of human PLXNA2 (NP_079455.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:CTRA GVEY RLLQ AAYL AKPG DSLA QAFN ITSQ DDVL FAIF SKGQ KQYH HPPD DSAL CAFP IRAI NLQI KERL QSCY QGEG NLEL NWLL GKDV QCTK APVP IDDN FCGL DINQ PLGG STPV EGLT LYTT SRDR MTSV ASYV YNGY SVVF VGTK SGKL KKIR ADGP PHGG VQYE MVSV LKDG SPIL RDMA FSID QRYL YVMS ERQV TRVP VESC EQYT TCGE CLSS GDPH CGWC ALHN MCSR RDKC QQAW EPNR FAAS ISQC V
Gene ID:5362
Uniprot:O75051
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:61kDa/211kDa
Observed MW:211kDa
Synonyms:PLXNA2, OCT, PLXN2, plexin-A2
Background:This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
NCBI Summary:This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]
UniProt Code:O75051
NCBI GenInfo Identifier:119613863
NCBI Gene ID:5362
NCBI Accession:
UniProt Related Accession:O75051
Molecular Weight:
NCBI Full Name:plexin A2
NCBI Synonym Full Names:plexin A2
NCBI Official Symbol:PLXNA2  
NCBI Official Synonym Symbols:OCT; PLXN2  
NCBI Protein Information:plexin-A2
UniProt Protein Name:
UniProt Gene Name:
Anti-PLXNA2 Antibody (CAB10087)Western blot analysis of extracts of various cell lines, using PLXNA2 antibody (CAB10087) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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