Cell Biology Antibodies 9
Anti-PLTP Antibody (CAB5628)
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- SKU:
- CAB5628
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PLTP Antibody |
| Antibody SKU: | CAB5628 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 142-441 of human PLTP (NP_872617.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, SW620 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 142-441 of human PLTP (NP_872617.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VLLN SLLD TVPV RSSV DELV GIDY SLMK DPVA STSN LDMD FRGA FFPL TERN WSLP NRAV EPQL QEEE RMVY VAFS EFFF DSAM ESYF RAGA LQLL LVGD KVPH DLDM LLRA TYFG SIVL LSPA VIDS PLKL ELRV LAPP RCTI KPSG TTIS VTAS VTIA LVPP DQPE VQLS SMTM DARL SAKM ALRG KALR TQLD LRRF RIYS NHSA LESL ALIP LQAP LKTM LQIG VMPM LNER TWRG VQIP LPEG INFV HEVV TNHA GFLT IGAD LHFA KGLR EVIE KNRP ADVR ASTA PTPS TAAV |
| Gene ID: | 5360 |
| Uniprot: | P55058 |
| Cellular Location: | Secreted |
| Calculated MW: | 44kDa/49kDa/54kDa |
| Observed MW: | 54kDa |
| Synonyms: | PLTP, BPIFE, HDLCQ9 |
| Background: | The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | PLTP: Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Lipid-binding; Secreted Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: extracellular region; extracellular space |
| NCBI Summary: | The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P55058 |
| NCBI GenInfo Identifier: | 1709662 |
| NCBI Gene ID: | 5360 |
| NCBI Accession: | P55058.1 |
| UniProt Secondary Accession: | P55058,Q8WTT1, Q9BR07, Q9BSH8, A8K006, B4DDD5, B4DRB4 E1P5N8, E7EV16, |
| UniProt Related Accession: | P55058 |
| Molecular Weight: | 44,847 Da |
| NCBI Full Name: | Phospholipid transfer protein |
| NCBI Synonym Full Names: | phospholipid transfer protein |
| NCBI Official Symbol: | PLTP |
| NCBI Official Synonym Symbols: | BPIFE; HDLCQ9 |
| NCBI Protein Information: | phospholipid transfer protein |
| UniProt Protein Name: | Phospholipid transfer protein |
| UniProt Synonym Protein Names: | Lipid transfer protein II |
| Protein Family: | Phospholipid transfer protein |
| UniProt Gene Name: | PLTP |
| UniProt Entry Name: | PLTP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PLTP antibody (CAB5628) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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