Cell Biology Antibodies 5

Anti-PLSCR4 Antibody (CAB14670)

(No reviews yet) Write a Review
SKU:
CAB14670
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PLSCR4 Antibody
Antibody SKU:CAB14670
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A-549, 22Rv1
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSGV VPTA PEQP AGEM ENQT KPPD PRPD APPE YNSH FLPG PPGT AVPP PTGY PGGL PMGY YSPQ QPST FPLY QPVG GIHP VRYQ PGKY PMPN QSVP ITWM PGPT PMAN CPPG LEYL VQLD NIHV LQHF EPLE MMTC FETN NRYD IKNN SDQM VYIV TEDT DDFT RNAY RTLR PFVL RVTD CMGR EIMT MQRP FRCT CCCF CCPS ARQE LEVQ CPPG VTIG FVAE HWNL CRAV YSIQ NEKK ENVM RVRG PCST YGCG SDSV FEVK SLDG IS
Gene ID:57088
Uniprot:Q9NRQ2
Cellular Location:Membrane, Single-pass type II membrane protein
Calculated MW:24kDa/37kDa
Observed MW:37kDa
Synonyms:PLSCR4, TRA1
Background:
UniProt Protein Function:PLSCR4: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: plasma membrane; integral to membrane

Molecular Function:phospholipid scramblase activity; protein binding; enzyme binding; calcium ion binding; CD4 receptor binding; SH3 domain binding

Biological Process: phospholipid scrambling

UniProt Code:Q9NRQ2
NCBI GenInfo Identifier:212276457
NCBI Gene ID:57088
NCBI Accession:Q9NRQ2.2
UniProt Secondary Accession:Q9NRQ2,Q2TTR3, Q658L3, Q6ZR73, Q7Z505, A8K2E9,
UniProt Related Accession:Q9NRQ2
Molecular Weight:24,797 Da
NCBI Full Name:Phospholipid scramblase 4
NCBI Synonym Full Names:phospholipid scramblase 4
NCBI Official Symbol:PLSCR4  
NCBI Official Synonym Symbols:TRA1  
NCBI Protein Information:phospholipid scramblase 4; PL scramblase 4; cell growth inhibiting protein 43; Ca(2+)-dependent phospholipid scramblase 4
UniProt Protein Name:Phospholipid scramblase 4
UniProt Synonym Protein Names:Ca(2+)-dependent phospholipid scramblase 4; Cell growth-inhibiting gene 43 protein; TRA1
Protein Family:Phospholipid scramblase
UniProt Gene Name:PLSCR4  
UniProt Entry Name:PLS4_HUMAN
Anti-PLSCR4 Antibody (CAB14670)Western blot analysis of extracts of various cell lines, using PLSCR4 antibody (CAB14670) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products